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Presenilin 1 抗体 (AA 10-80) (AbBy Fluor® 488)

Name: Presenilin 1 抗体 (AA 10-80) (AbBy Fluor® 488)
SKU: ABIN912121
Availability: OutOfStock

This anti-Presenilin 1 antibody is a 兔多克隆 antibody detecting Presenilin 1 in WB, IF (cc), IF (p) 和 FACS. Suitable for 人, 小鼠和大鼠.

产品编号 ABIN912121

发货至: 中国

Quick Overview for Presenilin 1 抗体 (AA 10-80) (AbBy Fluor® 488) (ABIN912121)

抗原

See all Presenilin 1 (PSEN1) 抗体

Presenilin 1 (PSEN1)

适用

人, 小鼠, 大鼠

宿主

兔

克隆类型

多克隆

标记

This Presenilin 1 antibody is conjugated to AbBy Fluor® 488

应用范围

Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS)

Discover our top product PSEN1 Primary Antibody

抗原表位
30

15

15

9

8

8

7

6

4

3

3

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2

2

2

2

2

1

1

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1

1
AA 10-80

交叉反应

人, 小鼠, 大鼠

预测反应

Dog,Cow,Pig,Rabbit

纯化方法

Purified by Protein A.

免疫原

KLH conjugated synthetic peptide derived from mouse Presenilin-1 NTF subunit

亚型

IgG
anti-Presenilin 1 (PSEN1) (AA 1-160) antibody
PSEN1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Presenilin 1 (PSEN1) (AA 330-359), (C-Term) antibody
PSEN1 适用: 人, 小鼠 WB, IHC (p), IF, FACS 宿主: 兔 Polyclonal RB2257 unconjugated

anti-Presenilin 1 (PSEN1) (AA 4-218) antibody
PSEN1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Presenilin 1 (PSEN1) (Middle Region) antibody
PSEN1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 犬, 马, 兔 WB, IHC, IP 宿主: 兔 Polyclonal unconjugated

anti-Presenilin 1 (PSEN1) (AA 1-160) antibody
PSEN1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated

anti-Presenilin 1 (PSEN1) (AA 300-349) antibody
PSEN1 适用: 人, 小鼠, 猴, Cow, Pig, 豚鼠, 马 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Presenilin 1 (PSEN1) (AA 107-156) antibody
PSEN1 适用: 人, 小鼠, 大鼠, 猴, Pig, 豚鼠, 犬, Bat, Hamster WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Presenilin 1 (PSEN1) (N-Term) antibody
PSEN1 适用: 人, 小鼠, 大鼠, Cow, 豚鼠, 犬, 马, 兔, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated

anti-Presenilin 1 (PSEN1) (AA 10-80) antibody
PSEN1 适用: 人, 小鼠, 大鼠 WB, ELISA, IF (cc), IF (p), IHC (p), FACS, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Presenilin 1 (PSEN1) (AA 10-80) antibody
PSEN1 适用: 小鼠 ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 小鼠 Polyclonal unconjugated

应用备注

FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

限制

仅限研究用
状态

Liquid

浓度

1 μg/μL

缓冲液

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

储存液

ProClin

注意事项

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

储存条件

-20 °C

储存方法

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

有效期

12 months
抗原

Presenilin 1 (PSEN1)

别名

Presenilin 1

背景

Synonyms: AD3, FAD, PS1, PS-1, S182, Presenilin-1, Protein S182, PSEN1, PSNL1
Background: Probable catalytic subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (beta-amyloid precursor protein). Requires the other members of the gamma-secretase complex to have a protease activity. May play a role in intracellular signaling and gene expression or in linking chromatin to the nuclear membrane. Stimulates cell-cell adhesion though its association with the E-cadherin/catenin complex. Under conditions of apoptosis or calcium influx, cleaves E-cadherin promoting the disassembly of the E-cadherin/catenin complex and increasing the pool of cytoplasmic beta-catenin, thus negatively regulating Wnt signaling. May also play a role in hematopoiesis.

基因ID

5663

UniProt

P49768

途径

Notch Signaling, EGFR Signaling Pathway, Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport