TMEM123 抗体 (PE-Cy5.5)
Quick Overview for TMEM123 抗体 (PE-Cy5.5) (ABIN911735)
抗原
See all TMEM123 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人, 小鼠, 大鼠
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预测反应
- Dog,Cow,Pig,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Porimin
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亚型
- IgG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- TMEM123 (Transmembrane Protein 123 (TMEM123))
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别名
- Porimin
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背景
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Synonyms: KCT3, Keratinocytes associated transmembrane protein 3, Pro oncosis receptor inducing membrane injury, Serine/threonine rich receptor, TMEM123, Transmembrane protein 123, PORIM_HUMAN.
Background: This gene encodes a highly glycosylated transmembrane protein with a high content of threonine and serine residues in its extracellular domain, similar to a broadly defined category of proteins termed mucins. Exposure of some cell types to anti PORIMIN (pro oncosis receptor inducing membrane injury) antibody, crosslinks this protein on the cell surface and induces a type of cell death termed oncosis. Oncosis is distinct from apoptosis and is characterized by a loss of cell membrane integrity without DNA fragmentation. This gene product is proposed to function as a cell surface receptor that mediates cell death.
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分子量
- 24kDa
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基因ID
- 114908
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途径
- Regulation of Cell Size
抗原
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