PNKP 抗体 (AA 51-160) (AbBy Fluor® 647)
Quick Overview for PNKP 抗体 (AA 51-160) (AbBy Fluor® 647) (ABIN911595)
抗原
See all PNKP 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-160
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human PNK1/PNKP
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亚型
- IgG
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- PNKP (Polynucleotide Kinase 3'-Phosphatase (PNKP))
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别名
- PNK1/PNKP
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背景
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Synonyms: Bunctional polynucleotide phosphatase/kinase, DEM 1, DEM1, DNA 5' kinase/3' phosphatase, PNK 1, PNK, PNK1, PNKP, Polynucleotide 5' hydroxyl kinase, Polynucleotide kinase 3 prime phosphatase, Polynucleotide kinase 3' phosphatase, Polynucleotide Kinase, PNKP_HUMAN.
Background: Mammalian PNK catalyzes the phosphorylation of DNA at 5'-hydroxyl termini and can dephosphorylate its 3'-phosphate termini. It plays an important function in DNA repair following ionizing radiation or oxidative damage.PNK has been reported to participate in the repair of DNA-double strand breaks via PARP-1-dependent nonhomologous end-joining.
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基因ID
- 11284
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途径
- DNA Damage Repair, Nucleotide Phosphorylation
抗原
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