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PDE4D 抗体 (AA 401-550) (AbBy Fluor® 647)

This anti-PDE4D antibody is a 兔 多克隆 antibody detecting PDE4D in WB 和 FACS. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN910479
发货至: 中国

Quick Overview for PDE4D 抗体 (AA 401-550) (AbBy Fluor® 647) (ABIN910479)

抗原

See all PDE4D 抗体
PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

适用

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  • 1
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人, 小鼠, 大鼠

宿主

  • 58
  • 2
  • 1

克隆类型

  • 55
  • 6
多克隆

标记

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This PDE4D antibody is conjugated to AbBy Fluor® 647

应用范围

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Western Blotting (WB), Flow Cytometry (FACS)
  • 抗原表位

    • 15
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    • 1
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    AA 401-550

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Dog,Cow,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human PDE4D

    亚型

    IgG
  • 应用备注

    FCM 1:20-100

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    PDE4D (phosphodiesterase 4D, cAMP-Specific (PDE4D))

    别名

    PDE4D

    背景

    Synonyms: cAMP specic 3',5' cyclic phosphodiesterase 4D, DKFZp686M11213, FLJ97311, cAMP specic 3' 5' cyclic phosphodiesterase 4D, cAMP specic phosphodiesterase 4D, cAMP specic phosphodiesterase PDE4D, cAMP specic phosphodiesterase PDE4D6, cyclic AMP phosphodiesterase, DPDE 3, DPDE3, Dunce like phosphodiesterase E3, HSPDE4D, PDE 43, PDE43, PDE4DN2, Phosphodiesterase 4D cAMP specic dunce Drosophila homolog phosphodiesterase E3, Phosphodiesterase 4D cAMP specic phosphodiesterase E3 dunce homolog Drosophila, Phosphodiesterase 4D cAMP specic, Phosphodiesterase 4D, cAMP specic dunce, Phosphodiesterase E3 dunce homolog Drosophila, STRK 1, STRK1.

    Background: Cyclic AMP-dependent phosphodiesterase type D (PDE4D) family is comprise of 5 variants (PDE4D1, D2, D3, D4 and D5). One or more PDE4D subtype variants are ubiquitously present in all mammalian cells. In CNS all five PDE4D subtype variants are expressed in varying ratios and their activity is regulated in tandem with GPCRs stimulation. Peripheral tissues also exhibit differential expression of PDE4D variants. PDE4D1/D2 mRNA levels rise in response to an increase in cAMP. Short term regulation of PDE4D variants involved PKA, MAP kinases and Erk2 phosphorylation that results in rapid change in their enzymatic activities. Other regulatory mechanism involved protein protein interactions with cytoskeletal scaffolding proteins.

    基因ID

    5144

    途径

    Cellular Response to Molecule of Bacterial Origin, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling
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