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ALIX 抗体 (AA 601-700) (Cy3)

This anti-ALIX antibody is a 兔 多克隆 antibody detecting ALIX in WB, IF (cc) 和 IF (p). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN910382
发货至: 中国

Quick Overview for ALIX 抗体 (AA 601-700) (Cy3) (ABIN910382)

抗原

See all ALIX (PDCD6IP) 抗体
ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))

适用

  • 80
  • 34
  • 32
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 70
  • 14
  • 1

克隆类型

  • 60
  • 24
多克隆

标记

  • 40
  • 4
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
This ALIX antibody is conjugated to Cy3

应用范围

  • 56
  • 25
  • 25
  • 25
  • 15
  • 14
  • 13
  • 13
  • 6
  • 6
  • 5
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 15
    • 14
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    AA 601-700

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human PDC6I

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    ALIX (PDCD6IP) (Programmed Cell Death 6 Interacting Protein (PDCD6IP))

    别名

    PDC6I

    背景

    Synonyms: AIP1, ALG 2 interacting protein 1, ALG-2-interacting protein 1, ALG2 interacting protein X, Alix, Apoptosis linked gene 2 interacting protein X, Dopamine receptor interacting protein 4, DRIP4, HP95, KIAA1375, MGC17003, PDC6I_HUMAN, PDCD6 interacting protein, PDCD6-interacting protein, PDCD6IP, Programmed cell death 6 interacting protein, Programmed cell death 6-interacting protein.

    Background: Class E VPS protein involved in concentration and sorting of cargo proteins of the multivesicular body (MVB) for incorporation into intralumenal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome. Binds to the phospholipid lysobisphosphatidic acid (LBPA) which is abundant in MVBs internal membranes. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and enveloped virus budding (HIV-1 and other lentiviruses). Appears to be an adapter for a subset of ESCRT-III proteins, such as CHMP4, to function at distinct membranes. Required for completion of cytokinesis. Involved in HIV-1 virus budding. Can replace TSG101 it its role of supporting HIV-1 release, this function implies the interaction with CHMP4B. May play a role in the regulation of both apoptosis and cell proliferation.

    基因ID

    10015

    途径

    p53 Pathway, EGFR Signaling Pathway, Sensory Perception of Sound, Cellular Response to Molecule of Bacterial Origin, Tube Formation
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