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LAP3 抗体 (AA 131-230) (Cy5.5)

This anti-LAP3 antibody is a 兔 多克隆 antibody detecting LAP3 in IF (cc) 和 IF (p). Suitable for 人.
产品编号 ABIN904529
发货至: 中国

Quick Overview for LAP3 抗体 (AA 131-230) (Cy5.5) (ABIN904529)

抗原

See all LAP3 抗体
LAP3 (Cytosol Aminopeptidase (LAP3))

适用

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宿主

  • 33
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克隆类型

  • 35
  • 3
多克隆

标记

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This LAP3 antibody is conjugated to Cy5.5

应用范围

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Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
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    AA 131-230

    预测反应

    Human,Mouse,Rat,Dog,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human LAP3

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    LAP3 (Cytosol Aminopeptidase (LAP3))

    别名

    LAP3

    背景

    Synonyms: Cytosol aminopeptidase, LAP 3, LAP, LAPEP, Leucine aminopeptidase 3, Leucyl aminopeptidase, PEPS, Peptidase S, Proline aminopeptidase, Prolyl aminopeptidase, AMPL_HUMAN.

    Background: LAP3 (leucine aminopeptidase 3), also known as LAPEP or PEPS, is a 519 amino acid protein that localizes to the cytoplasm and belongs to the peptidase M17 family. Existing as a homohexamer, LAP3 uses zinc as a cofactor to catalyze the release of an N-terminal proline from a target peptide and is, therefore, involved in the processing and turnover of intracellular proteins. Multiple isoforms of LAP3 exist due to alternative splicing events. The gene encoding LAP3 maps to human chromosome 4, which houses nearly 6 % of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.

    基因ID

    51056
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