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KEAP1 抗体 (AA 65-160) (AbBy Fluor® 350)

This anti-KEAP1 antibody is a 兔 多克隆 antibody detecting KEAP1 in WB, IF (cc) 和 IF (p). Suitable for 人, 小鼠, 大鼠, Pig 和 兔.
产品编号 ABIN903594
发货至: 中国
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中国
北京 101111
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Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for KEAP1 抗体 (AA 65-160) (AbBy Fluor® 350) (ABIN903594)

抗原

See all KEAP1 抗体
KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

适用

  • 99
  • 71
  • 39
  • 22
  • 18
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  • 5
  • 5
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  • 3
  • 3
  • 2
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人, 小鼠, 大鼠, Pig, 兔

宿主

  • 97
  • 10
  • 1

克隆类型

  • 86
  • 22
多克隆

标记

  • 52
  • 8
  • 6
  • 5
  • 2
  • 2
  • 2
  • 2
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  • 1
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This KEAP1 antibody is conjugated to AbBy Fluor® 350

应用范围

  • 88
  • 43
  • 39
  • 25
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  • 15
  • 10
  • 10
  • 7
  • 6
  • 6
  • 2
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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 15
    • 14
    • 12
    • 11
    • 10
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 65-160

    交叉反应

    人, 小鼠, Pig, 兔, 大鼠

    预测反应

    Dog,Cow

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human KEAP1

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))

    别名

    KEAP1

    背景

    Synonyms: INrf2, KLHL19, Kelch-like ECH-associated protein 1, Cytosolic inhibitor of Nrf2, Kelch-like protein 19, KEAP1, KIAA0132

    Background: Acts as a substrate adapter protein for the E3 ubiquitin ligase complex formed by CUL3 and RBX1 and targets NFE2L2/NRF2 for ubiquitination and degradation by the proteasome, thus resulting in the suppression of its transcriptional activity and the repression of antioxidant response element-mediated detoxifying enzyme gene expression. Retains NFE2L2/NRF2 and may also retain BPTF in the cytosol. Targets PGAM5 for ubiquitination and degradation by the proteasome.

    基因ID

    9817

    UniProt

    Q14145

    途径

    Maintenance of Protein Location
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