电话:
400-7060-959
传真:
+86 10 56315212-8813
电子邮件:
orders@antibodies-online.cn

KEAP1 抗体 (C-Term)

KEAP1 适用: 人, 小鼠, 大鼠, 兔, Cow, 犬, 马, 豚鼠, 斑马鱼 WB, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2775979
发货至: 中国
  • 抗原 See all KEAP1 抗体
    KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
    抗原表位
    • 20
    • 15
    • 15
    • 15
    • 10
    • 6
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    适用
    • 87
    • 56
    • 28
    • 20
    • 17
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    人, 小鼠, 大鼠, 兔, Cow, 犬, 马, 豚鼠, 斑马鱼
    宿主
    • 89
    • 7
    • 1
    克隆类型
    • 88
    • 9
    多克隆
    标记
    • 42
    • 10
    • 8
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This KEAP1 antibody is un-conjugated
    应用范围
    • 84
    • 50
    • 31
    • 26
    • 26
    • 16
    • 9
    • 9
    • 7
    • 6
    • 4
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    序列
    TWTFVAPMKH RRSALGITVH QGRIYVLGGY DGHTFLDSVE CYDPDTDTWS
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%
    产品特性
    This is a rabbit polyclonal antibody against KEAP1. It was validated on Western Blot and immunohistochemistry.
    纯化方法
    Protein A purified
    免疫原
    The immunogen is a synthetic peptide directed towards the C terminal region of human KEAP1
    Top Product
    Discover our top product KEAP1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 624 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Konishi, Baumgarten, Ishida, Saitoh, Anker, Springer: "Protein levels in Keap1-Nrf2 system in human failing heart." in: International journal of cardiology, Vol. 225, pp. 62-64, (2016) (PubMed).

  • 抗原
    KEAP1 (Kelch-Like ECH-Associated Protein 1 (KEAP1))
    别名
    KEAP1 (KEAP1 产品)
    别名
    INrf2 antibody, KLHL19 antibody, INRF2 antibody, mKIAA0132 antibody, Inrf2 antibody, fb36f11 antibody, keap1 antibody, wu:fb36f11 antibody, KEAP1 antibody, klhl19 antibody, zgc:171654 antibody, kelch like ECH associated protein 1 antibody, kelch-like ECH-associated protein 1 antibody, Kelch-like ECH-associated protein 1 antibody, kelch-like ECH-associated protein 1a antibody, kelch like ECH associated protein 1 L homeolog antibody, kelch-like ECH-associated protein 1b antibody, KEAP1 antibody, Keap1 antibody, keap1a antibody, keap1 antibody, keap1.L antibody, keap1b antibody
    背景
    KEAP1 contains KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase.This gene encodes a protein containing KELCH-1 like domains, as well as a BTB/POZ domain. Kelch-like ECH-associated protein 1 interacts with NF-E2-related factor 2 in a redox-sensitive manner and the dissociation of the proteins in the cytoplasm is followed by transportation of NF-E2-related factor 2 to the nucleus. This interaction results in the expression of the catalytic subunit of gamma-glutamylcysteine synthetase. Two alternatively spliced transcript variants encoding the same isoform have been found for this gene.
    Alias Symbols: INrf2, KIAA0132, KLHL19, MGC10630, MGC1114, MGC20887, MGC4407, MGC9454
    Protein Interaction Partner: OXR1, ZSCAN32, LSM3, KLHL3, FBXW11, MAPKBP1, NUDT4, DPP3, RBX1, ATG5, SQSTM1, PTMA, PRKAG1, NFE2L2, MAD2L1, GYPA, ETF1, BCL2, CUL3, RECK, UBC, PGAM5, FAM117B, WDR83, CCNB1IP1, HSP90AA1, XPO1, MCMBP, KEAP1, SLK, MCM3, IKBKB, AMER1, GPRASP2, PRKCE, NFE2L1,
    Protein Size: 624
    分子量
    70 kDa
    基因ID
    9817
    NCBI登录号
    NM_203500, NP_987096
    UniProt
    Q14145
    途径
    Maintenance of Protein Location
You are here:
客服