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Importin 9 抗体 (AA 601-729) (Biotin)

This anti-Importin 9 antibody (ABIN902692) is a Rabbit Polyclonal antibody detecting Importin 9 in WB, ELISA, IHC (p), IHC (fro). Suitable for Mouse.
产品编号 ABIN902692
发货至: 中国

Quick Overview for Importin 9 抗体 (AA 601-729) (Biotin) (ABIN902692)

抗原

See all Importin 9 (IPO9) 抗体
Importin 9 (IPO9)

适用

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小鼠

宿主

  • 58
  • 6
  • 1

克隆类型

  • 55
  • 10
多克隆

标记

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This Importin 9 antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
  • 抗原表位

    • 14
    • 8
    • 5
    • 5
    • 2
    • 2
    • 2
    • 1
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    • 1
    • 1
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    • 1
    • 1
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    • 1
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    • 1
    AA 601-729

    交叉反应

    小鼠

    预测反应

    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human Importin 9

    亚型

    IgG
  • 应用备注

    WB 1:300-5000
    IHC-P 1:200-400
    IHC-F 1:100-500

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C for 12 months.

    有效期

    12 months
  • 抗原

    Importin 9 (IPO9)

    别名

    Importin 9

    背景

    Synonyms: B cell antigen receptor Ig beta associated protein 1, BPM 90, BPM L, BPM-L, BPM90, BPML, IBAP 1, Imp 9, Importin 9, Importin9, Importin-9, Novel centrosomal protein RanBPM, RAN binding protein 9, Ran binding protein centrosomal, Ran binding protein M, Ran BP9, Ran-binding protein 9, Ran-binding protein M, RANB9_HUMAN, RanBP 7, RANBP 9, RanBP7, RanBP9, RanBPM.

    Background: May act as an adapter protein to couple membrane receptors to intracellular signaling pathways. May be involved in signaling of ITGB2/LFA-1 and other integrins. Enhances HGF-MET signaling by recruiting Sos and activating the Ras pathway. Involved in activation of androgen and glucocorticoid receptor in the presence of their cognate hormones. Stabilizes TP73 isoform Alpha, probably by inhibiting its ubiquitination, and increases its proapoptotic activity. Inhibits the kinase activity of DYRK1A and DYRK1B. Inhibits FMR1 binding to RNA.Tissue specificity: Ubiquitously expressed, with highest levels in testes, placenta, heart, and muscle, and lowest levels in lung. Within the brain, expressed predominantly by neurons in the gray matter of cortex, the granular layer of cerebellum and the Purkinje cells.

    基因ID

    10048

    途径

    Protein targeting to Nucleus
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