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ILP-2 抗体 (AA 141-236) (AbBy Fluor® 350)

This AbBy Fluor® 350-conjugated 兔 多克隆 anti-ILP-2 antibody specifically detects ILP-2 in IF (cc) 和 IF (p). The antibody is reactive with 大鼠 samples.
产品编号 ABIN902646
发货至: 中国
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Quick Overview for ILP-2 抗体 (AA 141-236) (AbBy Fluor® 350) (ABIN902646)

抗原

See all ILP-2 (BIRC8) 抗体
ILP-2 (BIRC8) (Baculoviral IAP Repeat-Containing 8 (BIRC8))

适用

  • 20
  • 11
  • 7
大鼠

宿主

  • 23
  • 2

克隆类型

  • 25
多克隆

标记

  • 12
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This ILP-2 antibody is conjugated to AbBy Fluor® 350

应用范围

  • 12
  • 12
  • 10
  • 8
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 4
    • 3
    • 2
    • 1
    AA 141-236

    交叉反应

    大鼠

    预测反应

    Human,Mouse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human ILP2

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    ILP-2 (BIRC8) (Baculoviral IAP Repeat-Containing 8 (BIRC8))

    别名

    ILP2

    背景

    Synonyms: Baculoviral IAP repeat containing 8, Baculoviral IAP repeat containing protein 8, Baculoviral IAP repeat-containing protein 8, BIRC 8, BIRC8, BIRC8 protein, BIRC8_HUMAN, hILP 2, hILP2, IAP like protein 2, IAP-like protein 2, ILP 2, ILP-2, Inhibitor of apoptosis like protein 2, Inhibitor of apoptosis-like protein 2, Testis specic inhibitor of apoptosis, Testis-specic inhibitor of apoptosis.

    Background: Protects against apoptosis mediated by BAX.Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family including IAP, XIAP/ILP-1/MIHA, and Livin/KIAP that bind to and inhibits specific proteases. A novel member in the IAP protein family was recently identified and designated ILP-2 for IAP-like protein-2 (1). ILP-2 has high homology to ILP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues (1). ILP-2, unlike ILP-1, has no inhibitory effect on Fas and TNF induced apoptosis, but potently inhibits apoptosis induced by overexpression of Bax or by coexpression of caspase-9 with Apaf-1. ILP-2 interacts with the processed caspase-9. These results suggest that ILP-2 is a novel IAP family member with restricted specificity for caspase-9.

    基因ID

    112401
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