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- 抗原 See all ILP-2 (BIRC8) 抗体
- ILP-2 (BIRC8) (Baculoviral IAP Repeat-Containing 8 (BIRC8))
- 适用
- 人, 大鼠, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ILP-2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
- 特异性
- ILP-2 antibody was raised with against a synthetic peptide corresponding to amino acids near the amino terminus of human ILP-2.
- 纯化方法
- Affinity chromatography purified via peptide column
- 免疫原
- Human ILP-2 Peptide
- 亚型
- IgG
- Top Product
- Discover our top product BIRC8 Primary Antibody
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anti-Baculoviral IAP Repeat-Containing 8 (BIRC8) (AA 2-13) antibody
BIRC8 适用: 人, 大鼠, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Baculoviral IAP Repeat-Containing 8 (BIRC8) (AA 1-236) antibodyBIRC8 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
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- 应用备注
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ELISA. Western Blot: 1 to 2 μg/mL. Human HepG2 or MOLT4 cell lysate can be used as a positivecontrol and a band at approximately 33 kDa can be detected. Immunocytochemistry.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - 限制
- 仅限研究用
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- 缓冲液
- PBS containing 0.02 % sodium azide.
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store the antibody undiluted at 2-8 °C.
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- 抗原
- ILP-2 (BIRC8) (Baculoviral IAP Repeat-Containing 8 (BIRC8))
- 别名
- BIRC8 / ILP2 (BIRC8 产品)
- 别名
- ILP-2 antibody, ILP2 antibody, hILP2 antibody, baculoviral IAP repeat containing 8 antibody, BIRC8 antibody
- 背景
- Apoptosis, or programmed cell death, is related to many diseases, such as cancer. Apoptosis is triggered by a variety of stimuli including members in the TNF family and prevented by the inhibitor of apoptosis (IAP) proteins. IAP proteins form a conserved gene family including IAP, XIAP/ILP-1/MIHA, and Livin/KIAP that bind to and inhibits specific proteases. A novel member in the IAP protein family was recently identified and designated ILP-2 for IAP-like protein-2 (1). ILP-2 has high homology to ILP-1, but is encoded by a distinct gene that is solely expressed in testis of tested normal human tissues (1). ILP-2, unlike ILP-1, has no inhibitory effect on Fas and TNF induced apoptosis, but potently inhibits apoptosis induced by overexpression of Bax or by coexpression of caspase-9 with Apaf-1. ILP-2 interacts with the processed caspase-9. These results suggest that ILP-2 is a novel IAP family member with restricted specificity for caspase-9.Synonyms: Baculoviral IAP repeat-containing protein 8, IAP-like protein 2, ILP-2, Inhibitor of apoptosis-like protein 2, Testis-specific inhibitor of apoptosis
- 基因ID
- 112401
- NCBI登录号
- NP_203127
- UniProt
- Q96P09
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