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HTRA2 抗体 (AA 355-458) (AbBy Fluor® 555)

This anti-HTRA2 antibody is a 兔 多克隆 antibody detecting HTRA2 in WB, IF (p) 和 IF (cc). Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN901506
发货至: 中国

Quick Overview for HTRA2 抗体 (AA 355-458) (AbBy Fluor® 555) (ABIN901506)

抗原

See all HTRA2 抗体
HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

适用

  • 100
  • 61
  • 58
  • 2
  • 1
人, 小鼠, 大鼠

宿主

  • 87
  • 14

克隆类型

  • 77
  • 24
多克隆

标记

  • 45
  • 8
  • 6
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
This HTRA2 antibody is conjugated to AbBy Fluor® 555

应用范围

  • 67
  • 41
  • 28
  • 25
  • 25
  • 15
  • 9
  • 8
  • 6
  • 6
  • 5
  • 4
  • 2
  • 1
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
  • 抗原表位

    • 15
    • 14
    • 10
    • 9
    • 7
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 355-458

    交叉反应

    人, 小鼠, 大鼠

    预测反应

    Dog,Cow,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human HtrA2

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    HTRA2 (HtrA Serine Peptidase 2 (HTRA2))

    别名

    HtrA2/Omi

    背景

    Synonyms: High temperature requirement protein a2, HTRA 2, HtrA like serine protease, HtrA serine peptidase 2, Omi stress regulated endoprotease, PARK 13, PARK13, Protease serine 25, PRSS 25, PRSS25, Serine protease 25, Serine protease HTRA2 mitochondrial, HtrA2, HTRA2_HUMAN, mitochondrial, Omi stress-regulated endoprotease, Serine protease HTRA2, Serine proteinase OMI, Serine protease htra2 mitochondrial precursor, Serine protease omi.

    Background: Serine protease that shows proteolytic activity against a non-specific substrate beta-casein. Promotes or induces cell death either by direct binding to and inhibition of BIRC proteins(also called inhibitor of apoptosis proteins, IAPs), leading to an increase in caspase activity, or by a BIRC inhibition-independent, caspase-independent and serine protease activity-dependent mechanism. Isoform 2 seems to be proteolytically inactive. [CATALYTIC ACTIVITY] Cleavage of non-polar aliphatic amino-acids at the P1 position, with a preference for Val, Ile and Met. At the P2 and P3 positions, Arg is selected most strongly with a secondary preference for other hydrophilic residues. [SUBUNIT] Homotrimer. Interacts with MXI2. The mature protein, but not the precursor, binds to BIRC2, BIRC3 and XIAP.

    基因ID

    27429

    UniProt

    O43464

    途径

    Positive Regulation of Endopeptidase Activity
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