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GZMB 抗体 (AA 21-130) (AbBy Fluor® 647)

GZMB 适用: 人, 小鼠 WB, FACS, IF (p), IF (cc) 宿主: 兔 Polyclonal AbBy Fluor® 647
产品编号 ABIN900009
发货至: 中国
  • 抗原 See all GZMB 抗体
    GZMB (Granzyme B (GZMB))
    抗原表位
    • 18
    • 15
    • 13
    • 10
    • 10
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 21-130
    适用
    • 131
    • 48
    • 24
    • 12
    • 4
    • 4
    • 3
    • 1
    人, 小鼠
    宿主
    • 84
    • 50
    • 2
    克隆类型
    • 82
    • 54
    多克隆
    标记
    • 82
    • 13
    • 7
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This GZMB antibody is conjugated to AbBy Fluor® 647
    应用范围
    • 71
    • 45
    • 41
    • 40
    • 19
    • 18
    • 17
    • 13
    • 12
    • 10
    • 9
    • 6
    • 6
    • 5
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
    特异性
    Specific towards Granzyme B and Granzyme H
    交叉反应
    人, 小鼠
    预测反应
    Rat,Cow,Pig
    纯化方法
    Purified by Protein A.
    免疫原
    KLH conjugated synthetic peptide derived from human GZMB
    亚型
    IgG
    Top Product
    Discover our top product GZMB Primary Antibody
  • 应用备注
    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 μg/μL
    缓冲液
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    有效期
    12 months
  • 抗原
    GZMB (Granzyme B (GZMB))
    别名
    Granzyme B (GZMB 产品)
    背景

    Synonyms: HLP, CCPI, CGL1, CSPB, SECT, CGL-1, CSP-B, CTLA1, CTSGL1, Granzyme B, C11, CTLA-1, Cathepsin G-like 1, Cytotoxic T-lymphocyte proteinase 2, Lymphocyte protease, Fragmentin-2, Granzyme-2, Human lymphocyte protein, T-cell serine protease 1-3E, GZMB, GRB, Granzyme B, Granzyme H

    Background: This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

    基因ID
    3002
    UniProt
    P10144
    途径
    Apoptosis, Caspase Cascade in Apoptosis
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