FKBP8 抗体 (AA 255-350) (Cy5)
Quick Overview for FKBP8 抗体 (AA 255-350) (Cy5) (ABIN897303)
抗原
See all FKBP8 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 255-350
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human,Dog,Cow,Horse,Chicken
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human FKBP38
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亚型
- IgG
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anti-FK506 Binding Protein 8, 38kDa (FKBP8) antibody
FKBP8 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 58-190) antibodyFKBP8 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 60-270) antibodyFKBP8 适用: 人 WB, IP, IF 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 110-329) antibodyFKBP8 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 93-339) antibodyFKBP8 适用: 人 WB, IHC, IP, ICC 宿主: 小鼠 Monoclonal 7-2# unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 42-276) antibodyFKBP8 适用: 人 IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 110-329) antibodyFKBP8 适用: 小鼠 WB, IHC, IP, ICC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 1-413) antibodyFKBP8 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 326-375) antibodyFKBP8 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, Cow, 山羊, 斑马鱼, 猴, Bat, Pig, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-FK506 Binding Protein 8, 38kDa (FKBP8) (AA 110-159) antibodyFKBP8 适用: 人, 小鼠, 大鼠, 犬, 豚鼠, 马, 猴, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- FKBP8 (FK506 Binding Protein 8, 38kDa (FKBP8))
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别名
- FKBP38
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背景
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Synonyms: 38 kDa FK 506 binding protein homolog, 38 kDa FK506-binding protein, 38 kDa FKBP, 38 kDa antibody FK506 binding protein 8, FK506 binding protein 8, 38 kDa, FK506 binding protein, 38 kDa, FK506-binding protein 8, FKBP 38, FKBP-38, FKBP-8, FKBP8, FKBP8_HUMAN, FKBPR38, hFKBP38, Peptidyl-prolyl cis-trans isomerase FKBP8, PPIase FKBP8, Rotamase, Sam11.
Background: Constitutively inactive PPiase, which becomes active when bound to calmodulin and calcium. Seems to act as a chaperone for BCL2, targets it to the mitochondria and modulates its phosphorylation state. The BCL2/FKBP8/calmodulin/calcium complex probably interferes with the binding of BCL2 to its targets. The active form of FKBP8 may therefore play a role in the regulation of apoptosis. Homomultimers or heteromultimers (Potential). Forms heterodimer with calmodulin. When activated by calmodulin and calcium, interacts with the BH4 domain of BCL2 and weakly with BCLX isoform Bcl-X(L). Does not bind and inhibit calcineurin. Interacts with HCV NS5A. Interacts with ZFYVE27, may negatively regulate ZFYVE27 phosphorylation.Tissue specificity: Widely expressed. Highest levels seen in the brain.
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基因ID
- 23770
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途径
- Autophagy
抗原
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