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NLRP1 抗体 (AA 301-400) (Cy3)

This anti-NLRP1 antibody is a 兔 多克隆 antibody detecting NLRP1 in WB, IF (cc) 和 IF (p). Suitable for 人 和 小鼠.
产品编号 ABIN886477
发货至: 中国

Quick Overview for NLRP1 抗体 (AA 301-400) (Cy3) (ABIN886477)

抗原

See all NLRP1 抗体
NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))

适用

  • 43
  • 18
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
人, 小鼠

宿主

  • 41
  • 2
  • 1

克隆类型

  • 44
多克隆

标记

  • 18
  • 4
  • 3
  • 3
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This NLRP1 antibody is conjugated to Cy3

应用范围

  • 29
  • 12
  • 12
  • 11
  • 7
  • 6
  • 5
  • 4
  • 3
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    AA 301-400

    交叉反应

    人, 小鼠

    预测反应

    Rat

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human CARD7/NALP1

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    NLRP1 (NLR Family, Pyrin Domain Containing 1 (NLRP1))

    别名

    CARD7

    背景

    Synonyms: LRR and PYD domains-containing protein 1, CARD 7, CARD7, Caspase recruitment domain protein 7, Caspase recruitment domain-containing protein 7, CLR17.1, Death effector filament forming Ced 4 like apoptosis protein, Death effector filament-forming ced-4-like apoptosis protein, DEFCAP, DEFCAP L/S, NAC alpha/beta/gamma/delta, NAC, NACHT, NACHT leucine rich repeat and PYD containing 1, NACHT leucine rich repeat and PYD pyrin domain containing 1, NACHT leucine rich repeat and pyrin domain containing 1, NACHT LRR and PYD containing protein 1, NALP 1, NALP1, NALP1_HUMAN, NLR family pyrin domain containing 1, NLRP 1, NLRP1, NLRP1 protein, Nucleotide binding domain and caspase recruitment domain, Nucleotide binding oligomerization domain leucine rich repeat and pyrin domain containing 1, Nucleotide-binding domain and caspase recruitment domain, PP 1044, PP1044.

    Background: This gene encodes a member of the Ced-4 family of apoptosis proteins. Ced-family members contain a caspase recruitment domain (CARD) and are known to be key mediators of programmed cell death. The encoded protein contains a distinct N-terminal pyrin-like motif, which is possibly involved in protein-protein interactions. This protein interacts strongly with caspase 2 and weakly with caspase 9. Overexpression of this gene was demonstrated to induce apoptosis in cells. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity of some variants has not been determined. [provided by RefSeq, Jul 2008].

    基因ID

    22861

    途径

    Positive Regulation of Endopeptidase Activity, Inflammasome
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