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CD80 抗体 (AA 251-321) (AbBy Fluor® 647)

This AbBy Fluor® 647-conjugated 兔 多克隆 anti-CD80 antibody specifically detects CD80 in WB, IF (cc) 和 IF (p). The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN884363
发货至: 中国
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Quick Overview for CD80 抗体 (AA 251-321) (AbBy Fluor® 647) (ABIN884363)

抗原

See all CD80 抗体
CD80

适用

  • 187
  • 106
  • 44
  • 11
  • 6
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  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 107
  • 97
  • 26
  • 20
  • 10
  • 7
  • 1

克隆类型

  • 182
  • 83
  • 2
多克隆

标记

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This CD80 antibody is conjugated to AbBy Fluor® 647

应用范围

  • 138
  • 102
  • 73
  • 46
  • 35
  • 22
  • 14
  • 12
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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 16
    • 14
    • 14
    • 12
    • 8
    • 7
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
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    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 251-321

    交叉反应

    人, 小鼠, 大鼠

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from rat CD80

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    CD80

    别名

    Cd80

    背景

    Synonyms: B7-1, Activation B7 1 antigen, Activation B71 antigen, B lymphocyte activation antigen B7, B7, BB1, CD 80, CD28 antigen ligand 1 B7 1 antigen, CD28 antigen ligand 1 B71 antigen, CD28LG, CD28LG1, CD80 antigen, CD80 antigen precursor,CD80 Molecule, Costimulatory factor CD80, CTLA 4 counter receptor B7.1, CTLA-4 counter-receptor B7.1, LAB 7, LAB7, T lymphocyte activation antigen CD80, CD80_MOUSE.

    Background: CD80 is a member of the Ig superfamily and serves as the ligand for two T cell molecules, CD28 and CTLA4. Interactions between CD28 and CD80 on activated B cells result in enhanced T cell activation. CD80 is rapidly induced on the surface of in vitro activated B cells, Epstein Barr Virus (EBV) transformed B cell lines, Burkitts lymphoma cell lines, freshly isolated follicular B lymphoma cells, T cells, and monocytes. It is also expressed at high levels in dendritic cells. It reacts weakly with a small proportion of non activated normal B cells and with HTLV1 infected T cells. CD80 does not react with peripheral monocytes, resting and activated normal T cells, T cell lines and T cell clones, nor with myelomonocytic cell lines.

    基因ID

    25408

    UniProt

    G3V671

    途径

    TCR Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints
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