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ATG12 抗体 (AA 101-187) (AbBy Fluor® 488)

This anti-ATG12 antibody is a 兔 多克隆 antibody detecting ATG12 in WB, IF (cc) 和 IF (p). Suitable for 小鼠 和 大鼠.
产品编号 ABIN882997
发货至: 中国

Quick Overview for ATG12 抗体 (AA 101-187) (AbBy Fluor® 488) (ABIN882997)

抗原

See all ATG12 抗体
ATG12 (Autophagy Related 12 (ATG12))

适用

  • 74
  • 35
  • 25
  • 6
  • 6
  • 6
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  • 5
  • 4
  • 4
  • 4
  • 4
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
小鼠, 大鼠

宿主

  • 70
  • 19
  • 2

克隆类型

  • 67
  • 24
多克隆

标记

  • 51
  • 6
  • 5
  • 5
  • 4
  • 4
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
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This ATG12 antibody is conjugated to AbBy Fluor® 488

应用范围

  • 68
  • 42
  • 30
  • 25
  • 16
  • 12
  • 12
  • 10
  • 9
  • 3
  • 3
  • 3
  • 1
  • 1
  • 1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 14
    • 9
    • 8
    • 6
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 101-187

    交叉反应

    小鼠, 大鼠

    预测反应

    Human,Dog,Cow,Pig,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic peptide derived from human ATG12

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    ATG12 (Autophagy Related 12 (ATG12))

    别名

    Apg12

    背景

    Synonyms: APG12, FBR93, APG12L, HAPG12, Ubiquitin-like protein ATG12, Autophagy-related protein 12, APG12-like, ATG12

    Background: Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG1 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. The ATG12-ATG5 conjugate also regulates negatively the innate antiviral immune response by blocking the type I IFN production pathway through direct association with RARRES3 and MAVS. Plays also a role in translation or delivery of incoming viral RNA to the translation apparatus.

    基因ID

    9140

    UniProt

    O94817

    途径

    Autophagy
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