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Ataxin 1 抗体 (pSer775) (AbBy Fluor® 647)

This anti-Ataxin 1 antibody is a 兔 多克隆 antibody detecting Ataxin 1 in IF (cc) 和 IF (p). Suitable for 大鼠.
产品编号 ABIN877000
发货至: 中国

Quick Overview for Ataxin 1 抗体 (pSer775) (AbBy Fluor® 647) (ABIN877000)

抗原

See all Ataxin 1 (ATXN1) 抗体
Ataxin 1 (ATXN1)

适用

  • 79
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  • 2
  • 1
  • 1
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  • 1
  • 1
  • 1
大鼠

宿主

  • 66
  • 52
  • 1

克隆类型

  • 66
  • 53
多克隆

标记

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  • 2
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  • 2
  • 1
  • 1
  • 1
  • 1
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  • 1
  • 1
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This Ataxin 1 antibody is conjugated to AbBy Fluor® 647

应用范围

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  • 1
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Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 27
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    • 3
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    • 2
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    • 1
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    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    pSer775

    交叉反应

    大鼠

    预测反应

    Human,Mouse,Dog,Cow,Pig,Horse,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human Ataxin-1 around the phosphorylation site of Ser775

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    Ataxin 1 (ATXN1)

    别名

    ATXN1

    背景

    Synonyms: ATXN1, ATX1, D6S504E, SCA1, Ataxin-1, Spinocerebellar ataxia type 1, ATX1_HUMAN.

    Background: The autosomal dominant cerebellar ataxias (ADCA) are a heterogeneous group of neurodegenerative disorders characterized by progressive degeneration of the cerebellum, brain stem and spinal cord. Clinically, ADCA has been divided into three groups: ADCA types I-III. ADCAI is genetically heterogeneous, with five genetic loci, designated spinocerebellar ataxia (SCA) 1, 2, 3, 4 and 6, being assigned to five different chromosomes. ADCAII, which always presents with retinal degeneration (SCA7), and ADCAIII often referred to as the `pure' cerebellar syndrome (SCA5), are most likely homogeneous disorders. Several SCA genes have been cloned and shown to contain CAG repeats in their coding regions. ADCA is caused by the expansion of the CAG repeats, producing an elongated polyglutamine tract in the corresponding protein. The expanded repeats are variable in size and unstable, usually increasing in size when transmitted to successive generations. The function of the ataxins is not known. This locus has been mapped to chromosome 6, and it has been determined that the diseased allele contains41-81 CAG repeats, compared to 6-39 in the normal allele, and is associated with spinocerebellar ataxia type 1 (SCA1). At least two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq].

    基因ID

    6310

    途径

    Synaptic Membrane
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