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beta Catenin 抗体 (pSer675) (AbBy Fluor® 488)

This anti-beta Catenin antibody is a 兔 多克隆 antibody detecting beta Catenin in FACS, IF (cc) 和 IF (p). Suitable for 人 和 大鼠.
产品编号 ABIN876803
发货至: 中国

Quick Overview for beta Catenin 抗体 (pSer675) (AbBy Fluor® 488) (ABIN876803)

抗原

See all beta Catenin (CATNB) 抗体
beta Catenin (CATNB) (Catenin, beta (CATNB))

适用

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宿主

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克隆类型

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多克隆

标记

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This beta Catenin antibody is conjugated to AbBy Fluor® 488

应用范围

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Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
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    pSer675

    交叉反应

    人, 大鼠

    预测反应

    Mouse,Cow,Sheep,Pig,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human Beta-Catenin around the phosphorylation site of Ser675

    亚型

    IgG
  • 应用备注

    FCM 1:20-100
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    beta Catenin (CATNB) (Catenin, beta (CATNB))

    别名

    Beta Catenin

    背景

    Synonyms: beta Catenin phospho S675, beta Catenin phospho Ser675, p-beta Catenin S675, p-beta Catenin Ser675, p-beta Catenin phospho S675, beta-catenin, beta catenin, CTNNB1, CHBCAT, CTNNB1, CTNNB, PRO2286, Cadherin associated protein, Catenin cadherin associated protein, beta 1, 88 kDa, Catenin beta 1, Catenin beta-1, CATNB, CTNB1_HUMAN, CTNNB, CTNNB1, DKFZp686D02253, FLJ25606, FLJ37923, b-catenin, OTTHUMP00000162082, OTTHUMP00000165222, OTTHUMP00000165223, OTTHUMP00000209288, OTTHUMP00000209289..

    Background: The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene.[provided by RefSeq, Oct 2009].

    基因ID

    1499

    途径

    Peptide Hormone Metabolism
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