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RACGAP1 抗体 (pSer387) (AbBy Fluor® 488)

The AbBy Fluor® 488-conjugated 兔 多克隆 anti-RACGAP1 antibody (ABIN875907) specifically detects RACGAP1 in WB, IF (p) 和 IF (cc). The antibody is reactive with 人 samples.
产品编号 ABIN875907
发货至: 中国
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Quick Overview for RACGAP1 抗体 (pSer387) (AbBy Fluor® 488) (ABIN875907)

抗原

See all RACGAP1 抗体
RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

适用

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人

宿主

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兔

克隆类型

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多克隆

标记

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This RACGAP1 antibody is conjugated to AbBy Fluor® 488

应用范围

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Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))
  • 抗原表位

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    pSer387

    原理

    phospho-RACGAP1 (Ser387) Polyclonal Antibody, AbBy Fluor-488 Conjugated

    交叉反应

    人, 小鼠

    预测反应

    Rat,Dog,Cow

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human RACGAP1 around the phosphorylation site of Ser387.

    亚型

    IgG
  • 应用备注

    WB(1:300-5000), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

    别名

    Racgap1

    背景

    Synonyms: RACGAP1 phospho S387, p-RACGAP1S387, p-RACGAP1Ser387, GAP, Gap1, GTPase activating protein, HsCYK 4, HsCYK4, ID GAP, KIAA1478, MgcRacGAP, Rac GTPase activating protein 1, RACGAP 1.

    Background: Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.

    基因ID

    29127

    途径

    Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling of Hepatocyte Growth Factor Receptor
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