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RACGAP1 抗体 (pSer387)

RACGAP1 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN6255287
发货至: 中国
  • 抗原 See all RACGAP1 抗体
    RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))
    抗原表位
    • 19
    • 15
    • 13
    • 8
    • 7
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer387
    适用
    • 73
    • 31
    • 25
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 2
    • 2
    人, 小鼠, 大鼠, 猴
    宿主
    • 82
    • 4
    • 2
    • 1
    克隆类型
    • 84
    • 5
    多克隆
    标记
    • 47
    • 6
    • 5
    • 5
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    This RACGAP1 antibody is un-conjugated
    应用范围
    • 81
    • 40
    • 34
    • 32
    • 26
    • 26
    • 15
    • 15
    • 9
    • 7
    • 6
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC)
    特异性
    Phospho-GTPase Activating Protein (Ser387) Antibody detects endogenous levels of GTPase Activating Protein only when phosphorylated at Serine 387
    交叉反应
    人, 猴, 小鼠, 大鼠
    纯化方法
    The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
    免疫原
    A synthesized peptide derived from human GTPase Activating Protein around the phosphorylation site of Serine 387
    亚型
    IgG
    Top Product
    Discover our top product RACGAP1 Primary Antibody
  • 应用备注
    WB 1:500-1:2000 IHC 1:50-1:200 IF/ICC 1:100-1:500
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    Rabbit IgG in phosphate buffered saline ,  pH 7.4, 150  mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C
    储存方法
    Store at -20 °C.Stable for 12 months from date of receipt
    有效期
    12 months
  • 抗原
    RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))
    别名
    GTPase Activating Protein (RACGAP1 产品)
    别名
    CYK4 antibody, HsCYK-4 antibody, ID-GAP antibody, MgcRacGAP antibody, cyk-4 antibody, id-gap antibody, mgcracgap antibody, RACGAP1 antibody, MGC121578 antibody, Gap antibody, RasGAP antibody, Rasa antibody, GAPX antibody, AI227039 antibody, AI327394 antibody, Band25 antibody, GTPase antibody, gtl11 antibody, mKIAA1478 antibody, wu:fb92c08 antibody, zgc:77839 antibody, Rac GTPase activating protein 1 antibody, rac GTPase-activating protein 1 antibody, Rac GTPase activating protein 1 L homeolog antibody, RAS p21 protein activator 1 antibody, Rac GTPase-activating protein 1 antibody, si:ch1073-416j23.1 antibody, RACGAP1 antibody, racgap1 antibody, racgap1.L antibody, racgap1.2.L antibody, racgap1.2 antibody, Rasa1 antibody, Racgap1 antibody, si:ch1073-416j23.1 antibody
    背景

    Description: Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Required for proper attachment of the midbody to the cell membrane during cytokinesis. Plays key roles in controlling cell growth and differentiation of hematopoietic cells through mechanisms other than regulating Rac GTPase activity. Also involved in the regulation of growth-related processes in adipocytes and myoblasts. May be involved in regulating spermatogenesis and in the RACGAP1 pathway in neuronal proliferation. Shows strong GAP (GTPase activation) activity towards CDC42 and RAC1 and less towards RHOA. Essential for the early stages of embryogenesis. May play a role in regulating cortical activity through RHOA during cytokinesis. May participate in the regulation of sulfate transport in male germ cells.

    Gene: RACGAP1

    分子量
    72kDa
    基因ID
    29127
    UniProt
    Q9H0H5
    途径
    Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling of Hepatocyte Growth Factor Receptor
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