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ILK 抗体 (pSer246) (AbBy Fluor® 647)

This anti-ILK antibody is a 兔 多克隆 antibody detecting ILK in WB, IF (cc) 和 IF (p). Suitable for 小鼠.
产品编号 ABIN875040
发货至: 中国

Quick Overview for ILK 抗体 (pSer246) (AbBy Fluor® 647) (ABIN875040)

抗原

See all ILK 抗体
ILK (Integrin-Linked Kinase (ILK))

适用

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小鼠

宿主

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克隆类型

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多克隆

标记

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This ILK antibody is conjugated to AbBy Fluor® 647

应用范围

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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

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    pSer246

    交叉反应

    小鼠

    预测反应

    Human,Rat,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human ILK-1 around the phosphorylation site of Ser246

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    ILK (Integrin-Linked Kinase (ILK))

    别名

    ILK-1

    背景

    Synonyms: ILK-1 phospho S246, ILK-1 phospho Ser246, p-ILK-1 Ser246, 59 kDa serine/threonine protein kinase, 59 kDa serine/threonine-protein kinase, ILK-2, ILK_HUMAN, Integrin linked Kinase, Integrin-linked protein kinase, DKFZp686F1765, EC 2.7.11.1, ILK 1, ILK 2, ILK, ILK1, ILK2, Integrin linked Kinase 2, Integrin linked protein kinase, p59, p59ILK.

    Background: The ILK protein is important in different biological pathways such as cell adhesion, anchorage-dependent cell cycle progression, oncogenic transformation, and growth factor signaling. The kinase activity of ILK is low in non-activated cells, its activity is stimulated by cell-ECM interactions and by certain growth factors. 3 Negative regulation of ILK is mediated by two phosphatases: PTEN, a tumor suppressor lipid sphatase, and ILKAP, a PP2C protein phosphatase. In tumor cells that do not express PTEN protein, ILK is constitutively active.

    基因ID

    3611

    途径

    Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration
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