CCDC116 抗体 (AA 155-260)
Quick Overview for CCDC116 抗体 (AA 155-260) (ABIN873296)
抗原
See all CCDC116 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 155-260
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交叉反应
- 人
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预测反应
- Mouse,Rat,Dog,Horse
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human CCDC116
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亚型
- IgG
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anti-Coiled-Coil Domain Containing 116 (CCDC116) (AA 1-300) antibody
CCDC116 适用: 人 ELISA, WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Coiled-Coil Domain Containing 116 (CCDC116) (C-Term) antibodyCCDC116 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- CCDC116 (Coiled-Coil Domain Containing 116 (CCDC116))
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别名
- CCDC116
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背景
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Synonyms: CC116_HUMAN, Ccdc116, Coiled-coil domain-containing protein 116.
Background: CCDC116 is a 515 amino acid protein that exists as two alternatively spliced isoforms. Encoded by a gene that maps to human chromosome 22q11.21, CCDC116 is induced by curcumin (diferulolylmethane), although its role is unclear. CCDC116 is significantly affected by dietary curcumin, which may have a protective role in inflammatory bowel disease (IBD) and may reduce the relapse rate in human ulcerative colitis (UC). As the second smallest human chromosome, chromosome 22 contains over 500 genes and about 49 million bases. Phelan-McDermid syndrome, Neurofibromatosis type 2 and autism are associated with chromosome 22. A schizophrenia susceptibility locus has been identified on chromosome 22 and studies show that 22q11 deletion symptoms include a high incidence of schizophrenia. Translocation between chromosomes 9 and 22 may lead to the formation of Philadelphia Chromosome and subsequent production of a novel fusion protein known as BCR-Abl, a potent cell proliferation activator found in several types of leukemia.
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基因ID
- 164592
抗原
-
