FMR1 抗体 (AA 112-210)
Quick Overview for FMR1 抗体 (AA 112-210) (ABIN873117)
抗原
See all FMR1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 112-210
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预测反应
- Human,Mouse,Rat,Dog,Cow,Pig,Chicken,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human FMRP
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亚型
- IgG
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anti-Fragile X Mental Retardation 1 (FMR1) (AA 36-279) antibody
FMR1 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 1C6 unconjugated
anti-Fragile X Mental Retardation 1 (FMR1) (AA 26-279) antibodyFMR1 适用: 人, 小鼠, 大鼠, 犬, 猴 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 2C3 unconjugated
anti-Fragile X Mental Retardation 1 (FMR1) antibodyFMR1 适用: 人 WB, IHC, IF, IHC (p), FACS 宿主: 小鼠 Monoclonal 3B4 unconjugated
anti-Fragile X Mental Retardation 1 (FMR1) (AA 121-220) antibodyFMR1 适用: 人 WB, ELISA, RNAi 宿主: 小鼠 Monoclonal 2D4 unconjugated
anti-Fragile X Mental Retardation 1 (FMR1) (AA 1-290) antibodyFMR1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Fragile X Mental Retardation 1 (FMR1) (AA 500-600) antibodyFMR1 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Fragile X Mental Retardation 1 (FMR1) (AA 116-130) antibodyVerified FMR1 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Fragile X Mental Retardation 1 (FMR1) (AA 121-220) antibodyFMR1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3E11 unconjugated
anti-Fragile X Mental Retardation 1 (FMR1) antibodyFMR1 适用: 人 IHC, ELISA, ICC 宿主: 小鼠 Monoclonal 4G9 unconjugated
anti-Fragile X Mental Retardation 1 (FMR1) (AA 20-48), (N-Term) antibodyFMR1 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB20964 unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- FMR1 (Fragile X Mental Retardation 1 (FMR1))
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别名
- FMR1
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背景
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Synonyms: FMR 1, FMR1, FMR1_HUMAN, FMRP, FMRP1, Fragile X mental retardation 1, Fragile X mental retardation 1 protein, FRAXA, POF, POF1, Protein FMR-1, Protein FMR1.
Background: Fragile X syndrome is the most frequent form of inherited mental retardation and is the result of transcriptional silencing of the FMR1 gene on the X chromosome. The FMR1 gene contains a distinct CpG dinucleotide repeat located in the 5' untranslated region of the gene. In fragile X syndrome this tandem repeat is substantially amplified and subjected to extensive methylation and enhanced transcriptional silencing. The FMR1 protein (or FMRP) is an RNA-binding protein that associates with polyribosomes and is a likely component of a messenger ribonuclear protein (mRNP) particle. It contains several features that are characteristics of RNA-binding proteins, including two hnRNPK homology (KH) domains and an RGG amino acid motif (RGG box). FMR1 localizes to both the nucleus and the cytoplasm and can also interact with two fragile X syndrome related factors, FXR1 and FXR2, which form heterodimers through their N-terminal coiled-coil domains. Since FMR1 contains both a nuclear localization signal and a nuclear export signal it is also implicated in the nucleocytoplasmic transport of mRNAs.
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基因ID
- 2332
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途径
- Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development
抗原
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