PHGDH 抗体 (AA 101-200)
Quick Overview for PHGDH 抗体 (AA 101-200) (ABIN872981)
抗原
See all PHGDH 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 101-200
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human PHGDH
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亚型
- IgG
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anti-phosphoglycerate Dehydrogenase (PHGDH) (AA 1-533) antibody
PHGDH 适用: 人 WB, ELISA, IHC (p), IF, IP 宿主: 小鼠 Monoclonal 4A3-1D6 unconjugated
anti-phosphoglycerate Dehydrogenase (PHGDH) (N-Term) antibodyKO Validated PHGDH 适用: 人 WB, IHC (p), IF, IP, IHC (fro), ICC 宿主: 兔 Polyclonal unconjugated
anti-phosphoglycerate Dehydrogenase (PHGDH) (AA 264-533) antibodyPHGDH 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-phosphoglycerate Dehydrogenase (PHGDH) (AA 140-168) antibodyPHGDH 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-phosphoglycerate Dehydrogenase (PHGDH) (AA 2-251) antibodyPHGDH 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-phosphoglycerate Dehydrogenase (PHGDH) (AA 249-277) antibodyPHGDH 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-phosphoglycerate Dehydrogenase (PHGDH) (AA 1-533) antibodyPHGDH 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-phosphoglycerate Dehydrogenase (PHGDH) (AA 1-533) antibodyPHGDH 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
anti-phosphoglycerate Dehydrogenase (PHGDH) (N-Term) antibodyPHGDH 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-phosphoglycerate Dehydrogenase (PHGDH) (AA 249-277) antibodyPHGDH 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB20883 unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- PHGDH (phosphoglycerate Dehydrogenase (PHGDH))
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别名
- PHGDH
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背景
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Synonyms: NLS, PDG, PGD, NLS1, PGAD, PGDH, SERA, 3PGDH, 3-PGDH, PHGDHD, HEL-S-113, D-3-phosphoglycerate dehydrogenase, PHGDH, PGDH3
Background: The survival and development of central neurons require the supply of trophic factors by glial cells. The trophic actions of glial cells on Purkinje neurons are mediated by L-serine and glycine, which are glia-derived trophic factors synthesized by 3PGDH (1). 3PGDH protein is 544 amino acids in length. Two distinct mRNA transcripts that encode for 3PGDH protein in normal human tissues are dominant 2.1 kb mRNA, which is highly expressed in prostate, testis, ovary, brain, liver, kidney, and pancreas, and weakly expressed in thymus, colon, and heart, and 710 bp mRNA, which is highly expressed in heart and skeletal muscle (2). 3PGDH is regulated at the transcriptional level depending on tissue specificity and cellular proliferative status (2). 3PGDH protein is also highly expressed in adult and fetal brain tissues (3). 3PGDH protein plays an important role in the metabolism, development, and function of the central nervous system (3) and its deficiency is a treatable congential error (4-5) that impairs L-serine biosynthesis which is characterized by congenital microcephaly, psychomotor retardation, and seizures (3).
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基因ID
- 26227
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UniProt
- O43175
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途径
- Metabolism of Steroid Hormones and Vitamin D, Warburg Effect
抗原
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