SKA1 抗体 (AA 181-255)
Quick Overview for SKA1 抗体 (AA 181-255) (ABIN872640)
抗原
See all SKA1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 181-255
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预测反应
- Human,Mouse,Rat,Dog,Cow,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human SKA1
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亚型
- IgG
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anti-Spindle and Kinetochore Associated Complex Subunit 1 (SKA1) (C-Term) antibody
SKA1 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Spindle and Kinetochore Associated Complex Subunit 1 (SKA1) (AA 61-134) antibodySKA1 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Spindle and Kinetochore Associated Complex Subunit 1 (SKA1) (AA 51-100) antibodySKA1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- SKA1 (Spindle and Kinetochore Associated Complex Subunit 1 (SKA1))
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别名
- SKA1
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背景
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Synonyms: Ska1, SKA1_HUMAN, Spindle and kinetochore associated complex subunit 1, Spindle and kinetochore associated protein 1, Spindle and kinetochore-associated protein 1, Spindle and KT kinetochore associated 1, Spindle and KT associated 1, C18orf24, MGC10200.
Background: Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the interaction with microtubules.
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途径
- M Phase
抗原
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