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- 抗原 See all SKA1 抗体
- SKA1 (Spindle and Kinetochore Associated Complex Subunit 1 (SKA1))
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抗原表位
- AA 61-134
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SKA1 antibody is un-conjugated
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应用范围
- ELISA, Immunohistochemistry (IHC)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Spindle and kinetochore-associated protein 1 protein (61-134AA)
- 亚型
- IgG
- Top Product
- Discover our top product SKA1 Primary Antibody
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anti-Spindle and Kinetochore Associated Complex Subunit 1 (SKA1) (C-Term) antibody
SKA1 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Spindle and Kinetochore Associated Complex Subunit 1 (SKA1) (AA 51-100) antibodySKA1 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: IHC:1:200-1:500,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- SKA1 (Spindle and Kinetochore Associated Complex Subunit 1 (SKA1))
- 别名
- SKA1 (SKA1 产品)
- 别名
- C18H18orf24 antibody, C18orf24 antibody, 2810433K01Rik antibody, AV117428 antibody, RGD1310784 antibody, spindle and kinetochore associated complex subunit 1 antibody, SKA1 antibody, ska1 antibody, Ska1 antibody
- 背景
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Background: Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation (PubMed:17093495, PubMed:19289083, PubMed:23085020). Required for timely anaphase onset during mitosis, when chromosomes undergo bipolar attachment on spindle microtubules leading to silencing of the spindle checkpoint (PubMed:17093495). The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies (PubMed:19289083). The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner (PubMed:19289083). Affinity for microtubules is synergistically enhanced in the presence of the ndc-80 complex and may allow the ndc-80 complex to track depolymerizing microtubules (PubMed:23085020). In the complex, it mediates the interaction with microtubules (PubMed:19289083, PubMed:23085020).
Aliases: 2810433K01Rik antibody, AV117428 antibody, C18orf24 antibody, MGC10200 antibody, Ska1 antibody, SKA1_HUMAN antibody, Spindle and kinetochore associated complex subunit 1 antibody, Spindle and kinetochore associated protein 1 antibody, Spindle and kinetochore-associated protein 1 antibody, Spindle and KT (kinetochore) associated 1 antibody, Spindle and KT associated 1 antibody
- UniProt
- Q96BD8
- 途径
- M Phase
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