PGLYRP1 抗体 (AA 65-150)
Quick Overview for PGLYRP1 抗体 (AA 65-150) (ABIN872537)
抗原
See all PGLYRP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 65-150
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预测反应
- Human,Mouse,Rat,Dog,Cow,Sheep,Pig,Horse,Rabbit
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human PGRPS
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亚型
- IgG
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anti-Peptidoglycan Recognition Protein 1 (PGLYRP1) (AA 22-196) antibody
PGLYRP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Peptidoglycan Recognition Protein 1 (PGLYRP1) (AA 19-182) antibodyPGLYRP1 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Peptidoglycan Recognition Protein 1 (PGLYRP1) (AA 18-183) antibodyPGLYRP1 适用: 大鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Peptidoglycan Recognition Protein 1 (PGLYRP1) (AA 22-196) antibodyPGLYRP1 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Peptidoglycan Recognition Protein 1 (PGLYRP1) antibodyPGLYRP1 适用: 人, 小鼠, 大鼠 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Peptidoglycan Recognition Protein 1 (PGLYRP1) (C-Term) antibodyVerified PGLYRP1 适用: 人 WB, IHC, ELISA 宿主: 山羊 Polyclonal unconjugated
anti-Peptidoglycan Recognition Protein 1 (PGLYRP1) antibodyPGLYRP1 适用: 人, 小鼠, 大鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Peptidoglycan Recognition Protein 1 (PGLYRP1) (AA 1-196) antibodyPGLYRP1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Peptidoglycan Recognition Protein 1 (PGLYRP1) (AA 1-196) antibodyPGLYRP1 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Peptidoglycan Recognition Protein 1 (PGLYRP1) (AA 165-180) antibodyPGLYRP1 适用: 人, 小鼠, 猴 WB, ICC, FACS 宿主: 小鼠 Monoclonal 188C424 unconjugated
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- PGLYRP1 (Peptidoglycan Recognition Protein 1 (PGLYRP1))
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别名
- PGRPS
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背景
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Synonyms: Peptidoglycan recognition protein 1, Peptidoglycan recognition protein, PGLYRP, PGLYRP1, PGRP, PGRP S, PGRP-PEN, PGRP-S, TAG7, TNFSF 3L, TNFSF3L, PGRP1_HUMAN.
Background: The primary immune recognition is based on structures common among invading pathogens. Bacterial surface molecules, such as lipopolysaccharide (LPS) and peptidoglycan (PGN), are known to elicit immune reactions ranging from cytokine release to fever. Recently, a family of proteins called peptidoglycan recognition protein (PGRP) has been identified in mouse and human that binds to peptidoglycans expressed on Gram-positive bacteria. Peptidoglycan (PGN) is an essential cell wall component of virtually all bacteria and, thus, it is an excellent target for recognition by the eukaryotic innate immune system. The PGRPs (PGRP-L, PGRPS, PGRPIA, and PGRP-I-beta) define a new family of human pattern recognition molecules. PGRP-L is primarily expressed in the liver. Although liver is not considered a primary immune organ, liver participates in host defenses by producing acute phase proteins (by hepatocytes) in response to infections and by clearing microorganisms from blood. PGRPS is present in neutrophils and inhibits growth of Gram-positive bacteria and, therefore, may function as a neutrophil antibacterial protein. However, PGRPS may have another, as yet unidentified function because in humans it is expressed in the bone marrow 50100 times higher than in neutrophils.
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基因ID
- 8993
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途径
- Activation of Innate immune Response
抗原
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