TBCD 抗体 (AA 401-500)
Quick Overview for TBCD 抗体 (AA 401-500) (ABIN872398)
抗原
See all TBCD 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- AA 401-500
-
交叉反应
- 小鼠
-
预测反应
- Human,Rat,Chicken,Rabbit
-
纯化方法
- Purified by Protein A.
-
免疫原
- KLH conjugated synthetic peptide derived from human TBCD/Beta tubulin cofactor D
-
亚型
- IgG
-
-
-
-
应用备注
-
WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 1 μg/μL
-
缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
-
储存液
- ProClin
-
注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
-
储存条件
- 4 °C,-20 °C
-
储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
-
有效期
- 12 months
-
-
- TBCD (Tubulin Folding Cofactor D (TBCD))
-
别名
- Beta tubulin cofactor D
-
背景
-
Synonyms: Beta tubulin cofactor D, Beta-tubulin cofactor D, KIAA0988, SSD 1, SSD-1, SSD1, tbcd, TBCD_HUMAN, tfcD, Tubulin folding cofactor D, Tubulin specic chaperone D, Tubulin-folding cofactor D, Tubulin-specic chaperone D.
Background: Tubulin-folding protein, involved in the first step of the tubulin folding pathway. Modulates microtubule dynamics by capturing GTP-bound beta-tubulin (TUBB). Acts as a GTPase-activating protein (GAP) for ARL2. Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes epithelial cell detachment, a process antagonized by ARL2. Induces tight adherens and tight junctions disassembly at the lateral cell membrane.
-
基因ID
- 6904
-
途径
- Cell-Cell Junction Organization
抗原
-