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TBCD 抗体 (AA 2-96) (FITC)

TBCD 适用: 人 宿主: 兔 Polyclonal FITC
产品编号 ABIN7173752
发货至: 中国
  • 抗原 See all TBCD 抗体
    TBCD (Tubulin Folding Cofactor D (TBCD))
    抗原表位
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 2-96
    适用
    • 9
    • 2
    • 1
    宿主
    • 8
    • 2
    克隆类型
    • 10
    多克隆
    标记
    • 8
    • 1
    • 1
    This TBCD antibody is conjugated to FITC
    应用范围
    请咨询
    交叉反应
    纯化方法
    >95%, Protein G purified
    免疫原
    Recombinant Human Tubulin-specific chaperone D protein (2-96AA)
    亚型
    IgG
    Top Product
    Discover our top product TBCD Primary Antibody
  • 限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    Preservative: 0.03 % Proclin 300
    Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    TBCD (Tubulin Folding Cofactor D (TBCD))
    别名
    TBCD (TBCD 产品)
    别名
    SSD-1 antibody, tfcD antibody, 2310057L06Rik antibody, A030005L14Rik antibody, mKIAA0988 antibody, tubulin folding cofactor D antibody, tubulin-specific chaperone d antibody, TBCD antibody, Tbcd antibody
    背景

    Background: Tubulin-folding protein implicated in the first step of the tubulin folding pathway and required for tubulin complex assembly. Involved in the regulation of microtubule polymerization or depolymerization, it modulates microtubule dynamics by capturing GTP-bound beta-tubulin (TUBB). Its ability to interact with beta tubulin is regulated via its interaction with ARL2. Acts as a GTPase-activating protein (GAP) for ARL2. Induces microtubule disruption in absence of ARL2. Increases degradation of beta tubulin, when overexpressed in polarized cells. Promotes epithelial cell detachment, a process antagonized by ARL2. Induces tight adherens and tight junctions disassembly at the lateral cell membrane (PubMed:10722852, PubMed:10831612, PubMed:11847227, PubMed:20740604, PubMed:27666370, PubMed:28158450). Required for correct assembly and maintenance of the mitotic spindle, and proper progression of mitosis (PubMed:27666370). Involved in neuron morphogenesis (PubMed:27666374).

    Aliases: Beta tubulin cofactor D antibody, Beta-tubulin cofactor D antibody, KIAA0988 antibody, SSD 1 antibody, SSD-1 antibody, SSD1 antibody, tbcd antibody, TBCD_HUMAN antibody, tfcD antibody, Tubulin folding cofactor D antibody, Tubulin specific chaperone D antibody, Tubulin-folding cofactor D antibody, Tubulin-specific chaperone D antibody

    UniProt
    Q9BTW9
    途径
    Cell-Cell Junction Organization
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