NOD1 抗体 (AA 51-150)
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北京 101111
Quick Overview for NOD1 抗体 (AA 51-150) (ABIN872332)
抗原
See all NOD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 51-150
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原理
- CARD4 Polyclonal Antibody
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交叉反应
- 小鼠, 大鼠
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预测反应
- Human
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human CARD4
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亚型
- IgG
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anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) (AA 923-951), (C-Term) antibody
NOD1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB29527 unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) (AA 1-160) antibodyNOD1 适用: 人, 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) (AA 923-951), (C-Term) antibodyNOD1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21998 unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) (AA 1-93) antibodyNOD1 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 3F10 unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) (C-Term) antibodyNOD1 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) (AA 923-951) antibodyNOD1 适用: 人 WB, IHC, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) (AA 26-953) antibodyNOD1 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) (AA 612-826) antibodyNOD1 适用: 人 WB, IHC, ICC, IP 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) antibodyNOD1 适用: 人, 小鼠 WB, IHC, FACS, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) antibodyNOD1 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB(1:300-5000),
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4C. Store at -20C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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: "The bacterial peptidoglycan-sensing molecule Pglyrp2 modulates brain development and behavior." in: Molecular psychiatry, Vol. 22, Issue 2, pp. 257-266, (2016) (PubMed).
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- NOD1 (Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1))
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别名
- CARD4
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背景
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Synonyms: CARD4, NLRC1, CLR7.1, Nucleotide-binding oligomerization domain-containing protein 1, Caspase recruitment domain-containing protein 4, NOD1
Background: Enhances caspase-9-mediated apoptosis. Induces NF-kappa-B activity via RIPK2 and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS). Forms an intracellular sensing system along with ARHGEF2 for the detection of microbial effectors during cell invasion by pathogens. Required for RHOA and RIPK2 dependent NF-kappa-B signaling pathway activation upon S.flexneri cell invasion. Involved not only in sensing peptidoglycan (PGN)-derived muropeptides but also in the activation of NF-kappa-B by Shigella effector proteins IpgB2 and OspB. Recruits NLRP10 to the cell membrane following bacterial infection.
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基因ID
- 10392
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UniProt
- Q9Y239
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途径
- Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades, Inflammasome
抗原
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