NOD1 抗体 (AA 2-31)
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北京 101111
Quick Overview for NOD1 抗体 (AA 2-31) (ABIN1169390)
抗原
See all NOD1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 2-31
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原理
- anti-Nod1 (human), pAb (AL184)
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特异性
- Recognizes human Nod1.
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产品特性
- Polyclonal Antibody. Recognizes human Nod1. Source: Rabbit. Applications: WB. Liquid. In PBS containing 10 % glycerol and 0.02 % sodium azide. Nod (CARD4) is a cytosolic pattern recognition molecule (PRRs) of the NLR (NOD-like receptor) family. Nod1 is widely expressed by many cell types and is implicated in sensing meso-diaminopimelic acid (meso-DAP)-containing PGN fragments, which are present in most Gramnegative bacteria and certain Gram-positive ones, like the Bacillus species. Upon activation, Nod1 initiates a pro-inflammatory response through NF-kappa signaling and is a key receptors in epithelial cells where it controls infections via the gastrointestinal system. Mutations in Nod1 have been reported to confer susceptibility to several inflammatory disorders including inflammatory bowel disease, atopic eczema and asthma.
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免疫原
- Synthetic peptide corresponding to aa 2-31 (E2EQGHSEMEIIPSESHPHIQLLKSNRELLV31) of human Nod1.
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anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) (AA 51-150) antibody
NOD1 适用: 人 WB, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) (AA 923-951), (C-Term) antibodyNOD1 适用: 人, 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB29527 unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) (AA 1-160) antibodyNOD1 适用: 人, 大鼠 WB, IHC, ICC 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) (AA 923-951), (C-Term) antibodyNOD1 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB21998 unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) (C-Term) antibodyNOD1 适用: 人 WB, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) (AA 923-951) antibodyNOD1 适用: 人 WB, IHC, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) (AA 1-93) antibodyNOD1 适用: 人 ELISA 宿主: 小鼠 Monoclonal 3F10 unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) (AA 26-953) antibodyNOD1 适用: 人 WB, ELISA, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) antibodyNOD1 适用: 人, 小鼠 WB, IHC, FACS, IF/ICC 宿主: 兔 Polyclonal unconjugated
anti-Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1) antibodyNOD1 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- In PBS containing 10 % glycerol and 0.02 % sodium azide.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- After opening, prepare aliquots and store at -20 °C.Avoid freeze/thaw cycles.
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储存条件
- 4 °C,-20 °C
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储存方法
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+4°C
-20°C
Stable for at least 1 year after receipt when stored at -20°C.
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有效期
- 12 months
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: "NOD protein expression and function in first trimester trophoblast cells." in: American journal of reproductive immunology (New York, N.Y. : 1989), Vol. 57, Issue 1, pp. 67-80, (2006) (PubMed).
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- NOD1 (Nucleotide-Binding Oligomerization Domain Containing 1 (NOD1))
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别名
- Nod1
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背景
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Alternate Names/Synonyms: CARD4, Caspase Recruitment Domain-containing Protein 4, Nucleotide-binding Oligomerization Domain-containing Protein 1
Product Description: Nod (CARD4) is a cytosolic pattern recognition molecule (PRRs) of the NLR (NOD-like receptor) family. Nod1 is widely expressed by many cell types and is implicated in sensing meso-diaminopimelic acid (meso-DAP)-containing PGN fragments, which are present in most Gramnegative bacteria and certain Gram-positive ones, like the Bacillus species. Upon activation, Nod1 initiates a pro-inflammatory response through NF-kappa signaling and is a key receptors in epithelial cells where it controls infections via the gastrointestinal system. Mutations in Nod1 have been reported to confer susceptibility to several inflammatory disorders including inflammatory bowel disease, atopic eczema and asthma.
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UniProt
- Q8BHB0
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途径
- Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades, Inflammasome
抗原
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