RACGAP1 抗体 (pSer387)
Quick Overview for RACGAP1 抗体 (pSer387) (ABIN872288)
抗原
See all RACGAP1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pSer387
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交叉反应
- 人, 小鼠
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预测反应
- Rat,Dog,Cow
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic phosphopeptide derived from human RACGAP1 around the phosphorylation site of Ser387.
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亚型
- IgG
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应用备注
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WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
- ProClin
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注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
- 12 months
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- RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))
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别名
- Racgap1
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背景
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Synonyms: RACGAP1 phospho S387, p-RACGAP1S387, p-RACGAP1Ser387, GAP, Gap1, GTPase activating protein, HsCYK 4, HsCYK4, ID GAP, KIAA1478, MgcRacGAP, Rac GTPase activating protein 1, RACGAP 1.
Background: Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO, RAC and CDC42. GTPase-activating proteins (GAPs) bind activated forms of Rho GTPases and stimulate GTP hydrolysis. Through this catalytic function, Rho GAPs negatively regulate Rho-mediated signals. GAPs may also serve as effector molecules and play a role in signaling downstream of Rho and other Ras-like GTPases.
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基因ID
- 29127
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途径
- Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling of Hepatocyte Growth Factor Receptor
抗原
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