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Estrogen Receptor alpha 抗体 (C-Term)

ESR1 适用: 人 IHC (p) 宿主: 兔 Monoclonal S21-V unconjugated
产品编号 ABIN870443
发货至: 中国
  • 抗原 See all Estrogen Receptor alpha (ESR1) 抗体
    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
    抗原表位
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    AA 580-594, C-Term
    适用
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    宿主
    • 351
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    克隆类型
    • 330
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    单克隆
    标记
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    This Estrogen Receptor alpha antibody is un-conjugated
    应用范围
    • 316
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    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    原理
    Anti-ER (Estrogen Receptor)
    特异性
    ER (Estrogen Receptor)
    免疫原
    Peptide derived from C-terminal sequence of human estrogen receptor alpha. Antibody recognizes the epitope between Gln580 - Thr594.
    克隆位点
    S21-V
    亚型
    IgG
    Top Product
    Discover our top product ESR1 Primary Antibody
  • 应用备注
    1:100 - 200
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    20 mM Tris-HCI, pH 8.0, Stabilizer: 20 mg/mL BSA, Preservative: 0.05 % sodium azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    +2 °C to +8 °C
  • 抗原
    Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
    别名
    Estrogen Receptor (ESR1 产品)
    背景
    Estrogen Receptor- α antibody stains nuclei of breast epithelial cells and some carcinomas, as well as endometrial epithelia and myometrium. By binding to the DNA, estrogen receptor-α regulates positively or negatively the gene expression. ER plays an important role in regulation of mammary gland growth and differentiation. Its overexpression can be found in more than 70 % of breast cancer.
    UniProt
    P03372
    途径
    Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
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