CD276 抗体
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- 抗原 See all CD276 抗体
- CD276
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This CD276 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Flow Cytometry (FACS), Immunofluorescence (IF)
- 纯化方法
- Ascitic fluid
- 免疫原
- Purified recombinant fragment of human CD276 expressed in E. Coli.
- 克隆位点
- 6A1
- 亚型
- IgG1
- Top Product
- Discover our top product CD276 Primary Antibody
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- 应用备注
- WB: 1/500 - 1/2000, IF: 1/200 - 1/1000, FC: 1/200-1/400, ELISA: Propose dilution 1/10000.
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 100g/100l
- 储存液
- Sodium azide
- 注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
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- 抗原
- CD276
- 别名
- CD276 (CD276 产品)
- 背景
- Costimulatory B7 molecules (e.g., B7-1, or CD80, MIM 112203) signal through CD28 (MIM 186760) family molecules such as CD28, CTLA4 (MIM 123890), and ICOS (MIM 604558). May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling. Synonyms: B7H3, B7-H3, 4Ig-B7-H3, CD276
- 分子量
- 57kDa
- 基因ID
- 80381
- 途径
- Cancer Immune Checkpoints
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