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CSK 抗体

This anti-CSK antibody is a 小鼠 单克隆 antibody detecting CSK in WB, ELISA, IF 和 FACS. Suitable for 人, 小鼠, 大鼠 和 猴.
产品编号 ABIN865513
发货至: 中国
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Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for CSK 抗体 (ABIN865513)

抗原

See all CSK 抗体
CSK (C-Src tyrosine Kinase (CSK))

适用

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人, 小鼠, 大鼠, 猴

宿主

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小鼠

克隆类型

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单克隆

标记

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This CSK antibody is un-conjugated

应用范围

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Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)

克隆位点

5F3
  • 纯化方法

    Ascitic fluid

    免疫原

    Purified recombinant fragment of human CSK expressed in E. Coli.

    亚型

    IgG1
  • 应用备注

    WB: 1/500 - 1/2000, IF: 1/200-1/1000, FC: 1/200-1/400, ELISA: Propose dilution 1/10000.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    100g/100l

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C
  • 抗原

    CSK (C-Src tyrosine Kinase (CSK))

    别名

    CSK

    背景

    Carboxy-terminal Src kinase (Csk) is a ubiquitously expressed nonreceptor tyrosine kinase that negatively regulates the Src family kinases (SFK) by phosphorylation of the SFK carboxy-terminal tyrosine. Phosphorylated carboxy-terminal tyrosine binds to the SH2 domain of SFK intramolecularly and leads to folding and inactivation of the SFK . This Csk-catalyzed SFK tyrosine phosphorylation is highly specific and exclusive. The SFK carboxy-terminal tyrosine is the only known physiological substrate of Csk . Tissue specificity: Expressed in lung and macrophages. Synonyms: MGC117393, CSK

    分子量

    50kDa

    基因ID

    1445

    途径

    TCR Signaling, EGFR Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events
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