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CSK 抗体

CSK 适用: 人, 小鼠, 大鼠, 猴 WB, ELISA, IF, FACS 宿主: 小鼠 Monoclonal 5F3 unconjugated
产品编号 ABIN865513
发货至: 中国
  • 抗原 See all CSK 抗体
    CSK (C-Src tyrosine Kinase (CSK))
    适用
    • 102
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    人, 小鼠, 大鼠, 猴
    宿主
    • 91
    • 10
    • 3
    小鼠
    克隆类型
    • 91
    • 12
    单克隆
    标记
    • 53
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    This CSK antibody is un-conjugated
    应用范围
    • 93
    • 40
    • 26
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    • 6
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    Western Blotting (WB), ELISA, Immunofluorescence (IF), Flow Cytometry (FACS)
    纯化方法
    Ascitic fluid
    免疫原
    Purified recombinant fragment of human CSK expressed in E. Coli.
    克隆位点
    5F3
    亚型
    IgG1
    Top Product
    Discover our top product CSK Primary Antibody
  • 应用备注
    WB: 1/500 - 1/2000, IF: 1/200-1/1000, FC: 1/200-1/400, ELISA: Propose dilution 1/10000.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    100g/100l
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
  • 抗原
    CSK (C-Src tyrosine Kinase (CSK))
    别名
    CSK (CSK 产品)
    背景
    Carboxy-terminal Src kinase (Csk) is a ubiquitously expressed nonreceptor tyrosine kinase that negatively regulates the Src family kinases (SFK) by phosphorylation of the SFK carboxy-terminal tyrosine. Phosphorylated carboxy-terminal tyrosine binds to the SH2 domain of SFK intramolecularly and leads to folding and inactivation of the SFK . This Csk-catalyzed SFK tyrosine phosphorylation is highly specific and exclusive. The SFK carboxy-terminal tyrosine is the only known physiological substrate of Csk . Tissue specificity: Expressed in lung and macrophages. Synonyms: MGC117393, CSK
    分子量
    50kDa
    基因ID
    1445
    途径
    TCR Signaling, EGFR Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events
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