CSK 抗体
Our Local Distributor
北京 101111
Quick Overview for CSK 抗体 (ABIN865513)
抗原
See all CSK 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
-
-
纯化方法
- Ascitic fluid
-
免疫原
- Purified recombinant fragment of human CSK expressed in E. Coli.
-
亚型
- IgG1
-
-
-
-
应用备注
- WB: 1/500 - 1/2000, IF: 1/200-1/1000, FC: 1/200-1/400, ELISA: Propose dilution 1/10000.
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- 100g/100l
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
-
- CSK (C-Src tyrosine Kinase (CSK))
-
别名
- CSK
-
背景
- Carboxy-terminal Src kinase (Csk) is a ubiquitously expressed nonreceptor tyrosine kinase that negatively regulates the Src family kinases (SFK) by phosphorylation of the SFK carboxy-terminal tyrosine. Phosphorylated carboxy-terminal tyrosine binds to the SH2 domain of SFK intramolecularly and leads to folding and inactivation of the SFK . This Csk-catalyzed SFK tyrosine phosphorylation is highly specific and exclusive. The SFK carboxy-terminal tyrosine is the only known physiological substrate of Csk . Tissue specificity: Expressed in lung and macrophages. Synonyms: MGC117393, CSK
-
分子量
- 50kDa
-
基因ID
- 1445
-
途径
- TCR Signaling, EGFR Signaling Pathway, Cell-Cell Junction Organization, CXCR4-mediated Signaling Events
抗原
-