TAB2 抗体
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北京 101111
Quick Overview for TAB2 抗体 (ABIN865507)
抗原
See all TAB2 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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纯化方法
- Ascitic fluid
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免疫原
- Purified recombinant fragment of human TAB2 expressed in E. Coli.
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亚型
- IgG1
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应用备注
- WB: 1/500 - 1/2000, FC: 1/200-1/400, ELISA: Propose dilution 1/10000.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 100g/100l
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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- TAB2 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2))
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别名
- TAB2
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背景
- The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts. Synonyms: CHTD2, FLJ21885, KIAA0733, MAP3K7IP2, TAB2
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分子量
- 80kDa
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基因ID
- 23118
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途径
- TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Ubiquitin Proteasome Pathway
抗原
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