ILK 抗体 (pThr173)
Quick Overview for ILK 抗体 (pThr173) (ABIN802143)
抗原
See all ILK 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
 - pThr173
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交叉反应
 - 人, 大鼠
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预测反应
 - Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit
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纯化方法
 - Purified by Protein A.
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免疫原
 - KLH conjugated synthetic phosphopeptide derived from human ILK-1 around the phosphorylation site of Thr173
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亚型
 - IgG
 
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应用备注
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                        WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - 
                                            
限制
 - 仅限研究用
 
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状态
 - Liquid
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浓度
 - 1 μg/μL
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缓冲液
 - 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
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储存液
 - ProClin
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注意事项
 - This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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储存条件
 - 4 °C,-20 °C
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储存方法
 - Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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有效期
 - 12 months
 
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- ILK (Integrin-Linked Kinase (ILK))
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别名
 - ILK-1
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背景
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Synonyms: P59, ILK-1, ILK-2, p59ILK, HEL-S-28, Integrin-linked protein kinase, 59 kDa serine/threonine-protein kinase, ILK, ILK1, ILK2
Background: Receptor-proximal protein kinase regulating integrin-mediated signal transduction. May act as a mediator of inside-out integrin signaling. Focal adhesion protein part of the complex ILK-PINCH. This complex is considered to be one of the convergence points of integrin- and growth factor-signaling pathway. Could be implicated in mediating cell architecture, adhesion to integrin substrates and anchorage-dependent growth in epithelial cells. Phosphorylates beta-1 and beta-3 integrin subunit on serine and threonine residues, but also AKT1 and GSK3B.
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基因ID
 - 3611
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UniProt
 - Q13418
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途径
 - Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Maintenance of Protein Location, Skeletal Muscle Fiber Development, Smooth Muscle Cell Migration
 
抗原
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