CD41, CD61 抗体
-
- 抗原 See all CD41, CD61 抗体
- CD41, CD61 (CD41,CD61)
-
适用
- 人
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This CD41, CD61 antibody is un-conjugated
-
应用范围
- Flow Cytometry (FACS), Immunoprecipitation (IP), Enzyme Immunoassay (EIA), Immunohistochemistry (Frozen Sections) (IHC (fro)), Functional Studies (Func)
- 免疫原
- Human platelets
- 克隆位点
- P2
- 亚型
- IgG1
- Top Product
- Discover our top product CD41, CD61 Primary Antibody
-
-
- 应用备注
- Optimal working dilution should be determined by the investigator.
- 限制
- 仅限研究用
-
- 溶解方式
- Restore with 1 mL distilled water.
- 浓度
- 0.2 mg/mL (prior to lyophilization)
- 缓冲液
- PBS buffer with 1 mg/mL BSA as stabilizer without preservatives
- 储存液
- Without preservative
- 储存条件
- 4 °C
- 储存方法
- Store at 2 - 8 °C.
-
- 抗原
- CD41, CD61 (CD41,CD61)
- Abstract
- CD41, CD61 产品
- 背景
- Integrin alpha 2b (CD41) is a calcium-dependent, noncovalently associated heterodimer and contains a heavy chain (GPIIb alpha) and a light chain (GPIIb beta) linked by a single disulfide bond. The Integrin alpha 2B chain interacts with the Integrin beta 3 subunit/CD61 to form the platelet glycoprotein complex, gpIIb/IIIa. It is expressed on platelets and megakaryocytes. Ligands for the gpIIb/IIIa heterodimer include fibrinogen, von Willebrand factor, fibronectin, vitronectin, and thrombospondin. The gpIIb/IIIa complex is the major Integrin on platelets and is important for platelet adhesion and aggregation.Synonyms: CD41, CD61, GP2B, GP3A, GPIIb, GPIIb-IIIa, GPalpha IIb, ITGA2B, ITGAB, ITGB3, Integrin alpha-IIb, Integrin beta-3, Platelet membrane glycoprotein IIb
-