DARC 抗体 (N-Term)
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Quick Overview for DARC 抗体 (N-Term) (ABIN784594)
抗原
See all DARC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects endogenous levels of total CD234 protein.
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纯化方法
- Immunoaffinity Chromatography
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免疫原
- Synthetic peptide from human DARC. Remarks: Antigen Modification: N-Terminus
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亚型
- IgG
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS (without Mg2+, Ca2+), pH 7.4, 150 mM Sodium Chloride, 0.02 % Sodium Azide and 50 % Glycerol
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C or lower. Avoid freeze-thaw cycles.
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- DARC (Duffy Blood Group, Chemokine Receptor (DARC))
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别名
- CD234 / DARC
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背景
- Duffy blood group antigens, part of the Chemokine Receptor family, appear to be multimeric erythrocyte-membrane protein receptors composed of different subunits. A glycoprotein, GPD, is the major subunit of the protein complex. Other components include the Rh, PGM1, Fy, and PEPC proteins. Duffy antigen is expressed by red blood cells, by postcapillary venule endothelium throughout the body, except in the liver, and by Purkinje cells of the cerebellum. Duffy negativity (lack of Duffy expression in bone marrow) has been linked to protection against malaria. In erythrocytes, the chemokines interleukin-8 and melanoma growth stimulatory activity (MGSA) activate Duffy antigen.Synonyms: Duffy antigen/chemokine receptor, FY, Fy glycoprotein, GPD, Glycoprotein D, GpFy, Plasmodium vivax receptor
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基因ID
- 2532
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NCBI登录号
- NP_001116423
抗原
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