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PDGFRA 抗体 (AA 1035-1053)

PDGFRA 适用: 人, 小鼠, 大鼠, 小鸡, 非洲爪蟾 WB, IHC (p), IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN784591
发货至: 中国
  • 抗原 See all PDGFRA 抗体
    PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
    抗原表位
    • 24
    • 16
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    • 11
    • 10
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    AA 1035-1053
    适用
    • 243
    • 126
    • 71
    • 19
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 小鸡, 非洲爪蟾
    宿主
    • 218
    • 40
    • 4
    • 1
    克隆类型
    • 210
    • 53
    多克隆
    标记
    • 115
    • 20
    • 18
    • 14
    • 14
    • 12
    • 8
    • 8
    • 8
    • 8
    • 8
    • 8
    • 4
    • 4
    • 4
    • 4
    • 4
    • 2
    This PDGFRA antibody is un-conjugated
    应用范围
    • 175
    • 108
    • 66
    • 54
    • 54
    • 41
    • 38
    • 24
    • 23
    • 14
    • 7
    • 7
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    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
    序列
    C-GKRNRHSSQT SEESAIETG Remarks: Antigen Modificati on: Amino acids 1035-1053
    特异性
    Recognizes Human PDGF Receptor Type A, doublet, Mr 150/170 kDa.
    交叉反应 (详细)
    Species reactivity (expected):Chicken, Frog, Mouse, Rat, Zebrafish.
    Species reactivity (tested):Human.
    纯化方法
    Immunoaffinity Chromatography
    免疫原
    Synthetic peptide KLH-conjugated corresponding to amino acids 1035-1053 of Human PDGF.
    亚型
    IgG
    Top Product
    Discover our top product PDGFRA Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    0.2 M Tris-Glycine, pH 7.4 containing 0.12 M Sodium Chloride and 0.05 % Sodium Azide as preservative
    储存液
    Sodium azide
    注意事项
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C/-20 °C
    储存方法
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid freeze-thaw cycles.
  • 抗原
    PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))
    别名
    CD140a / PDGFRA (PDGFRA 产品)
    别名
    AI115593 antibody, CD140a antibody, Pdgfr-2 antibody, APDGFR antibody, PDGFACE antibody, CD140A antibody, PDGFR-2 antibody, PDGFR2 antibody, RHEPDGFRA antibody, PDGFR antibody, PDGFR-A antibody, platelet derived growth factor receptor alpha antibody, platelet derived growth factor receptor, alpha polypeptide antibody, platelet-derived growth factor receptor, alpha polypeptide L homeolog antibody, platelet-derived growth factor receptor, alpha polypeptide antibody, PDGFRA antibody, Pdgfra antibody, pdgfra.L antibody
    背景
    Platelet-derived Growth Factor Receptor Alpha (PDGFR alpha), a member of the a PDGF Receptor tyrosine kinase family, is a mediator of the biological actions of platelet-derived growth factor (PDGF). PDGF binding to PDGF receptors result in stimulation of cell growth, chemotaxis, and cell shape changes. Unlike PDGFR beta, PDGFR alpha can bind to both PDGF subunits. PDGFR alpha has been implicated in the development of spina bifida. In various mouse models, deregulated PDGFR alpha expression was found to result in congenital neural tube defects. In humans, various PDGFRA promoter haplotypes have been associated with neural tube defects.Synonyms: Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, PDGF Receptor alpha, PDGF-R-alpha
    基因ID
    5156
    NCBI登录号
    NP_006197
    途径
    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
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