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PDGFRA 抗体 (AA 1035-1053)

This 兔 多克隆 antibody specifically detects PDGFRA in WB, IHC (p) 和 IP. It exhibits reactivity toward 人, 小鼠, 大鼠, 小鸡 和 非洲爪蟾.
产品编号 ABIN784591
发货至: 中国
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Quick Overview for PDGFRA 抗体 (AA 1035-1053) (ABIN784591)

抗原

See all PDGFRA 抗体
PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))

适用

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人, 小鼠, 大鼠, 小鸡, 非洲爪蟾

宿主

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克隆类型

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多克隆

标记

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This PDGFRA antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP)
  • 抗原表位

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    AA 1035-1053

    序列

    C-GKRNRHSSQT SEESAIETG Remarks: Antigen Modificati on: Amino acids 1035-1053

    特异性

    Recognizes Human PDGF Receptor Type A, doublet, Mr 150/170 kDa.

    交叉反应 (详细)

    Species reactivity (expected):Chicken, Frog, Mouse, Rat, Zebrafish.
    Species reactivity (tested):Human.

    纯化方法

    Immunoaffinity Chromatography

    免疫原

    Synthetic peptide KLH-conjugated corresponding to amino acids 1035-1053 of Human PDGF.

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    缓冲液

    0.2 M Tris-Glycine, pH 7.4 containing 0.12 M Sodium Chloride and 0.05 % Sodium Azide as preservative

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer. Avoid freeze-thaw cycles.
  • 抗原

    PDGFRA (Platelet Derived Growth Factor Receptor alpha (PDGFRA))

    别名

    CD140a / PDGFRA

    背景

    Platelet-derived Growth Factor Receptor Alpha (PDGFR alpha), a member of the a PDGF Receptor tyrosine kinase family, is a mediator of the biological actions of platelet-derived growth factor (PDGF). PDGF binding to PDGF receptors result in stimulation of cell growth, chemotaxis, and cell shape changes. Unlike PDGFR beta, PDGFR alpha can bind to both PDGF subunits. PDGFR alpha has been implicated in the development of spina bifida. In various mouse models, deregulated PDGFR alpha expression was found to result in congenital neural tube defects. In humans, various PDGFRA promoter haplotypes have been associated with neural tube defects.Synonyms: Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, PDGF Receptor alpha, PDGF-R-alpha

    基因ID

    5156

    NCBI登录号

    NP_006197

    途径

    RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Platelet-derived growth Factor Receptor Signaling
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