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RGS14 抗体 (AA 504-516)

This 兔 多克隆 antibody specifically detects RGS14 in WB 和 IHC (p). It exhibits reactivity toward 人.
产品编号 ABIN784000
发货至: 中国
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Room 801-803
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Quick Overview for RGS14 抗体 (AA 504-516) (ABIN784000)

抗原

See all RGS14 抗体
RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

适用

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宿主

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克隆类型

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多克隆

标记

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This RGS14 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 抗原表位

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    AA 504-516

    特异性

    Recognizes RGS14.
    Cellular Localization: Membrane

    交叉反应 (详细)

    Species reactivity (tested):Human.

    纯化方法

    Antigen-Affinity Chromatography.

    免疫原

    Synthetic peptide contain a sequence corresponding to a region within amino acids 504 and 516 of Human RGS14

    亚型

    IgG
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.93 mg/mL

    缓冲液

    0.1 M Tris, 0.1 M Glycine, 10 % Glycerol ( pH 7) containing 0.01 % Thimerosal as a preservative.

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody undiluted (in aliquots) at -20 °C.
  • 抗原

    RGS14 (Regulator of G-Protein Signaling 14 (RGS14))

    别名

    RGS14

    背景

    This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.Synonyms: Regulator of G-protein signaling 14

    基因ID

    10636, 9606

    途径

    Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Platelet-derived growth Factor Receptor Signaling
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