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RGS14 抗体 (AA 230-510)

RGS14 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7167592
发货至: 中国
  • 抗原 See all RGS14 抗体
    RGS14 (Regulator of G-Protein Signaling 14 (RGS14))
    抗原表位
    • 15
    • 8
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
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    • 1
    AA 230-510
    适用
    • 46
    • 33
    • 25
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
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    宿主
    • 57
    • 4
    • 1
    克隆类型
    • 60
    • 2
    多克隆
    标记
    • 31
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
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    • 2
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    This RGS14 antibody is un-conjugated
    应用范围
    • 52
    • 23
    • 13
    • 13
    • 8
    • 5
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    ELISA, Immunohistochemistry (IHC)
    交叉反应
    纯化方法
    Antigen Affinity Purified
    免疫原
    Recombinant Human Regulator of G-protein signaling 14 protein (230-510AA)
    亚型
    IgG
    Top Product
    Discover our top product RGS14 Primary Antibody
  • 应用备注
    Recommended dilution: IHC:1:20-1:200,
    限制
    仅限研究用
  • 状态
    Liquid
    缓冲液
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    -20 °C,-80 °C
    储存方法
    Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
  • 抗原
    RGS14 (Regulator of G-Protein Signaling 14 (RGS14))
    别名
    RGS14 (RGS14 产品)
    别名
    RPIP1 antibody, MGC80558 antibody, RGS14 antibody, rgs14 antibody, wu:fi04g12 antibody, regulator of G protein signaling 14 antibody, regulator of G-protein signaling 14 antibody, regulator of G-protein signaling 14 L homeolog antibody, regulator of G-protein signalling 14 antibody, regulator of G protein signaling 14a antibody, RGS14 antibody, Rgs14 antibody, rgs14.L antibody, rgs14 antibody, rgs14a antibody
    背景

    Background: Regulates G protein-coupled receptor signaling cascades. Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Besides, modulates signal transduction via G protein alpha subunits by functioning as a GDP-dissociation inhibitor (GDI). Has GDI activity on G(i) alpha subunits GNAI1 and GNAI3, but not on GNAI2 and G(o) alpha subunit GNAO1. Has GAP activity on GNAI0, GNAI2 and GNAI3. May act as a scaffold integrating G protein and Ras/Raf MAPkinase signaling pathways. Inhibits platelet-derived growth factor (PDGF)-stimulated ERK1/ERK2 phosphorylation, a process depending on its interaction with HRAS and that is reversed by G(i) alpha subunit GNAI1. Acts as a positive modulator of microtubule polymerisation and spindle organization through a G(i)-alpha-dependent mechanism. Plays a role in cell division. Required for the nerve growth factor (NGF)-mediated neurite outgrowth. Involved in stress resistance. May be involved in visual memory processing capacity and hippocampal-based learning and memory.

    Aliases: Highly similar to rap1/rap2 interacting protein antibody, OTTHUMP00000223586 antibody, OTTHUMP00000223587 antibody, Regulation of G protein signaling 14 antibody, Regulator of G protein signaling 14 antibody, Regulator of G protein signalling 14 antibody, Regulator of G-protein signaling 14 antibody, RGS 14 antibody, RGS14 antibody, RGS14_HUMAN antibody

    UniProt
    O43566
    途径
    Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Platelet-derived growth Factor Receptor Signaling
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