TRAIL 抗体
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北京 101111
Quick Overview for TRAIL 抗体 (ABIN783968)
抗原
See all TRAIL (TNFSF10) 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- Recognizes TRAIL.
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交叉反应 (详细)
- Species reactivity (tested):Mouse.
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纯化方法
- Affinity Chromatography employing an immobilized Murine TRAIL matrix
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免疫原
- Highly pure recombinant Murine TRAIL.
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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溶解方式
- Restore in sterile water to a concentration of 0.1-1.0 mg/mL.
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缓冲液
- PBS, pH 7.2 without preservatives
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储存液
- Without preservative
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the lyophilized antibody at -20 °C. Following reconstitution it is stable for two weeks at 2-8 °C. Frozen aliquots are stable for 6 months when stored at -20 °C.
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有效期
- 6 months
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- TRAIL (TNFSF10) (Tumor Necrosis Factor (Ligand) Superfamily, Member 10 (TNFSF10))
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别名
- CD253 / TRAIL
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背景
- TRAIL is a cytotoxic protein, which activates rapid apoptosis in tumor cells, but not in normal cells. TRAIL induced apoptosis is achieved through binding to two death-signaling receptors, DR4 and DR5. These receptors belong to the TNFR superfamily of transmembrane proteins and contain a cytoplasmic Death domain which activates the cell's apoptotic machinery.Synonyms: APO2L, Apo-2 ligand, Apo-2L, TNF-related apoptosis-inducing ligand, TNFSF10, Tumor necrosis factor ligand superfamily member 10
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基因ID
- 10850
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NCBI登录号
- NP_033451
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途径
- Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
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