TLR3 抗体
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北京 101111
Quick Overview for TLR3 抗体 (ABIN783847)
抗原
See all TLR3 抗体适用
宿主
克隆类型
标记
应用范围
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特异性
- This antibody detects ~103 kDa of TLR3.
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交叉反应 (详细)
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Affinity chromatography
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免疫原
- Synthetic peptide surrounding amino acid 805 of mouse TLR3
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 0.5 mg/mL
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缓冲液
- Phosphate buffered saline (PBS), pH 7.2, containing 30 % clycerol, 0.5 % BSA, and 0.1 %thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Upon receipt, store at -20 °C. For long term storage, aliquot and store at -70 °C.
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- TLR3 (Toll-Like Receptor 3 (TLR3))
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别名
- CD283 / TLR3
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背景
- To date, at least ten members of the Toll family have been identified. TLRs recognize molecular patterns associated with microbial pathogens and induce antimicrobial immune response. TLR3 recognizes double-stranded (ds) RNA, induces the activation of NF-kB, through MyD88-dependent and -independent pathways, and the production of type I interferons (IFNs). Similar to several other members of the TLR family, TLR3 has been reported to be expressed at a very low level on the surface of human fibroblast cell lines.Synonyms: Toll-like receptor 3
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基因ID
- 7098
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NCBI登录号
- NP_003256
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UniProt
- O15455
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途径
- TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
抗原
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