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TLR3 抗体

This 山羊 多克隆 antibody specifically detects TLR3 in WB. It exhibits reactivity toward 人, 小鼠 和 大鼠.
产品编号 ABIN783847
发货至: 中国
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Quick Overview for TLR3 抗体 (ABIN783847)

抗原

See all TLR3 抗体
TLR3 (Toll-Like Receptor 3 (TLR3))

适用

  • 98
  • 71
  • 28
  • 6
  • 2
  • 1
  • 1
  • 1
人, 小鼠, 大鼠

宿主

  • 83
  • 32
  • 10
  • 4
  • 1
山羊

克隆类型

  • 85
  • 45
多克隆

标记

  • 57
  • 17
  • 15
  • 10
  • 7
  • 5
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TLR3 antibody is un-conjugated

应用范围

  • 78
  • 40
  • 37
  • 35
  • 21
  • 17
  • 15
  • 13
  • 13
  • 12
  • 8
  • 5
  • 4
  • 2
  • 2
  • 1
  • 1
Western Blotting (WB)
  • 特异性

    This antibody detects ~103 kDa of TLR3.

    交叉反应 (详细)

    Species reactivity (tested):Human, mouse, rat

    纯化方法

    Affinity chromatography

    免疫原

    Synthetic peptide surrounding amino acid 805 of mouse TLR3
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.5 mg/mL

    缓冲液

    Phosphate buffered saline (PBS), pH 7.2, containing 30 % clycerol, 0.5 % BSA, and 0.1 %thimerosal

    储存液

    Thimerosal (Merthiolate)

    注意事项

    This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Upon receipt, store at -20 °C. For long term storage, aliquot and store at -70 °C.
  • 抗原

    TLR3 (Toll-Like Receptor 3 (TLR3))

    别名

    CD283 / TLR3

    背景

    To date, at least ten members of the Toll family have been identified. TLRs recognize molecular patterns associated with microbial pathogens and induce antimicrobial immune response. TLR3 recognizes double-stranded (ds) RNA, induces the activation of NF-kB, through MyD88-dependent and -independent pathways, and the production of type I interferons (IFNs). Similar to several other members of the TLR family, TLR3 has been reported to be expressed at a very low level on the surface of human fibroblast cell lines.Synonyms: Toll-like receptor 3

    基因ID

    7098

    NCBI登录号

    NP_003256

    UniProt

    O15455

    途径

    TLR signaling, Activation of Innate immune Response, Hepatitis C, Toll-Like Receptors Cascades
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