RWDD3 抗体 (N-Term)
This 兔 多克隆 anti-RWDD3 antibody specifically detects RWDD3 in WB 和 EIA. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
1 image
产品编号 ABIN783831
发货至:
中国
Contact our Customer Service for availability and price in your country.
Contact Info
Our Local Distributor
中国
北京 101111
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
Quick Overview for RWDD3 抗体 (N-Term) (ABIN783831)
抗原
See all RWDD3 抗体
RWDD3
(RWD Domain Containing 3 (RWDD3))
适用
人, 小鼠, 大鼠
宿主
兔
克隆类型
多克隆
标记
This RWDD3 antibody is un-conjugated
应用范围
Western Blotting (WB), Enzyme Immunoassay (EIA)
-
-
抗原表位
- N-Term
-
特异性
- This antibody reacts to RWD domain containing 3.
-
纯化方法
- Affinity chromatography
-
免疫原
- 17 amino acid peptide from near the amino terminus of human RWDD3.
-
-
anti-RWD Domain Containing 3 (RWDD3) (C-Term) antibody
RWDD3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-RWD Domain Containing 3 (RWDD3) (N-Term) antibodyRWDD3 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
-
-
应用备注
- Optimal working dilution should be determined by the investigator.
-
限制
- 仅限研究用
-
-
-
缓冲液
- PBS containing 0.02 % sodium azide as preservative
-
储存液
- Sodium azide
-
注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
储存条件
- 4 °C
-
储存方法
- Store the antibody undiluted at 2-8 °C.
-
-
- RWDD3 (RWD Domain Containing 3 (RWDD3))
-
别名
- RWDD3
-
背景
- RWDD3 (RSUME), a small RWD-containing protein, has a central role in sumoylation by enhancing SUMO conjugation in the regulatory network of immune inflammatory signals. RWDD3 increases Ikbeta sumoylation and stability. In addition, RWDD3 inhibits TNF-alpha-induced kB-LUC (Luciferase) reporter activity, showing the functional consequence of Ikbeta increased stability. RSUME-enhanced sumoylation of Ikbeta leads to the inhibition of NF-kbeta activity on two well-known inflammatory genes, IL-8 and cyclooxygenase-2 (Cox-2) and therefore may also favor anti-inflammatory pathways. Expression of RWDD3 was induced under hypoxic conditions and it has a potential role during vascularization. Both BMP-4 and RWDD3 may be interesting targets for inhibiting steps involved in pituitary tumorigenesis.Synonyms: RSUME, RWD domain-containing protein 3, RWD-containing sumoylation enhancer
-
基因ID
- 25950
-
NCBI登录号
- NP_001121614
-
UniProt
- Q9Y3V2
抗原
-
You are here:
