CDC23 抗体 (Center)
Quick Overview for CDC23 抗体 (Center) (ABIN783825)
抗原
See all CDC23 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Center
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交叉反应 （详细）
- Species reactivity (tested):Human, mouse, rat
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 17 amino acid peptide near the center of human APC8
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anti-Cell Division Cycle 23 (CDC23) (AA 366-597) antibody
CDC23 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 23 (CDC23) (AA 50-150) antibodyCDC23 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 23 (CDC23) antibodyCDC23 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 23 (CDC23) (AA 491-591) antibodyCDC23 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 1F3 unconjugated
anti-Cell Division Cycle 23 (CDC23) (Internal Region) antibodyCDC23 适用: 人, 小鼠, 猴 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 23 (CDC23) (Internal Region) antibodyCDC23 适用: 人, 小鼠 WB, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 23 (CDC23) antibodyCDC23 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Cell Division Cycle 23 (CDC23) (AA 62-142) antibodyCDC23 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 23 (CDC23) (C-Term) antibodyCDC23 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 猴, 非洲爪蟾, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
anti-Cell Division Cycle 23 (CDC23) (AA 101-150) antibodyCDC23 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔, 猴, 非洲爪蟾, 小鸡, 斑马鱼, Bat, Pig WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1.0 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- -20 °C
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储存方法
- Store the antibody (in aliquots) at -20 °C.
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- CDC23 (Cell Division Cycle 23 (CDC23))
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别名
- CDC23 / APC8
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背景
- Cell cycle regulated protein ubiquitination and degradation within subcellular domains is thought to be essential for the normal progression of mitosis. APC8 is a highly conserved component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. APC/C is responsible for degrading anaphase inhibitors, mitotic cyclins, and spindle-associated proteins ensuring that events of mitosis take place in proper sequence. The individual APC/C components mRNA and protein levels are expressed at approximately the same levels in most tissues and cell lines, suggesting that they perform their functions as part of a complex. In Drosophila, silencing of APC8 results in developmental delay and pupal lethality with elevated levels of apoptosis, high mitotic index, and delayed or blocked mitosis.Synonyms: ANAPC8, Anaphase-promoting complex subunit 8, Cell division cycle protein 23 homolog, Cyclosome subunit 8
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基因ID
- 8697
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NCBI登录号
- NP_004652
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UniProt
- Q9UJX2
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途径
- Protein targeting to Nucleus
抗原
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