ZFYVE26 抗体 (C-Term)
Quick Overview for ZFYVE26 抗体 (C-Term) (ABIN783824)
抗原
See all ZFYVE26 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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特异性
- This antibody reacts to ZFYVE26.
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纯化方法
- Affinity chromatography
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免疫原
- 16 amino acid peptide near the carboxy terminus of human SPG15.
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anti-Zinc Finger, FYVE Domain Containing 26 (ZFYVE26) (AA 2306-2473) antibody
ZFYVE26 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, FYVE Domain Containing 26 (ZFYVE26) (C-Term) antibodyZFYVE26 适用: 人, 小鼠, 大鼠 ELISA, WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Zinc Finger, FYVE Domain Containing 26 (ZFYVE26) (N-Term) antibodyZFYVE26 适用: 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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浓度
- 1,0 mg/mL
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缓冲液
- PBS containing 0.02 % sodium azide as preservative
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C
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储存方法
- Store the antibody undiluted at 2-8 °C.
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- ZFYVE26 (Zinc Finger, FYVE Domain Containing 26 (ZFYVE26))
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别名
- ZFYVE26
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背景
- Hereditary spastic paraplegias (HSPs) are genetically and phenotypically heterogeneous disorders. Spastic paraplegia with thinning of the corpus callosum (ARHSP-TCC) is a relatively frequent form of complicated hereditary spastic paraplegia in which mental retardation and muscle stiffness at onset are followed by slowly progressive paraparesis and cognitive deterioration. SPG15 is the second gene known to be responsible for ARHSP-TCC in the Italian population. Mutations in this gene are associated with autosomal recessive spastic paraplegia-15. SPG15 encodes a protein containing a FYVE zinc finger binding domain which is thought to target these proteins to membrane lipids through interaction with phospholipids in the membrane. SPG15 mRNA is widely distributed in human tissues, as well as in rat embryos, suggesting a possible role for this protein during embryonic development. SPG15 co-localizes partially with endoplasmic reticulum and endosome markers, suggesting a role in intracellular trafficking. Multiple isoforms of SPG15 are known to exist.Synonyms: KIAA0321, Zinc finger FYVE domain-containing protein 26
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基因ID
- 23503
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NCBI登录号
- NP_056161
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UniProt
- Q68DK2
抗原
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