TMEM59 抗体 (N-Term)
Quick Overview for TMEM59 抗体 (N-Term) (ABIN783793)
抗原
See all TMEM59 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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特异性
- This antibody detects TMEM59 at N-term.
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交叉反应 （详细）
- Species reactivity (tested):Human
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纯化方法
- Affinity chromatography purified via peptide column
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免疫原
- 16 amino acid peptide near amino terminus of human TMEM59
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anti-Transmembrane Protein 59 (TMEM59) antibody
TMEM59 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 59 (TMEM59) (AA 59-201) antibodyTMEM59 适用: 人 WB, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 59 (TMEM59) (AA 36-230) antibodyTMEM59 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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缓冲液
- PBS containing 0.02 % sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- TMEM59 (Transmembrane Protein 59 (TMEM59))
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别名
- TMEM59
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背景
- Processing of the amyloid precursor protein (APP) by two different proteases, called alpha- and beta-secretase, is a central regulatory event in the generation of the amyloid beta peptide (Abeta), which has a key role in Alzheimer disease (AD) pathogenesis. TMEM59, a Golgi-localized protein, modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP. It inhibits APP transport and shedding.Synonyms: C1orf8, HSPC001, Liver membrane-bound protein, Transmembrane protein 59
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基因ID
- 9528
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NCBI登录号
- NP_004863
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UniProt
- Q9BXS4
抗原
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