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- 抗原 See all TMEM59 抗体
- TMEM59 (Transmembrane Protein 59 (TMEM59))
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抗原表位
- AA 59-201
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TMEM59 antibody is un-conjugated
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应用范围
- Western Blotting (WB), ELISA, Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- >95%, Protein G purified
- 免疫原
- Recombinant Human Transmembrane protein 59 protein (59-201AA)
- 亚型
- IgG
- Top Product
- Discover our top product TMEM59 Primary Antibody
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anti-Transmembrane Protein 59 (TMEM59) antibody
TMEM59 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Transmembrane Protein 59 (TMEM59) (AA 36-230) antibodyTMEM59 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- Recommended dilution: WB:1:500-1:5000, IF:1:50-1:200,
- 限制
- 仅限研究用
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- 状态
- Liquid
- 缓冲液
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Preservative: 0.03 % Proclin 300
Constituents: 50 % Glycerol, 0.01M PBS, pH 7.4 - 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- -20 °C,-80 °C
- 储存方法
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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- 抗原
- TMEM59 (Transmembrane Protein 59 (TMEM59))
- 别名
- TMEM59 (TMEM59 产品)
- 别名
- Tmem59 antibody, C1orf8 antibody, HSPC001 antibody, 1110001M20Rik antibody, 3110046P06Rik antibody, AI256529 antibody, D4Ertd20e antibody, MTDCF1 antibody, ORF18 antibody, transmembrane protein 59 antibody, tmem59 antibody, Tmem59 antibody, TMEM59 antibody
- 背景
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Background: Acts as a regulator of autophagy in response to S.aureus infection by promoting activation of LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C). Acts by interacting with ATG16L1, leading to promote a functional complex between LC3 and ATG16L1 and promoting LC3 lipidation and subsequent activation of autophagy (PubMed:27273576, PubMed:23376921). Modulates the O-glycosylation and complex N-glycosylation steps occurring during the Golgi maturation of several proteins such as APP, BACE1, SEAP or PRNP (PubMed:20427278). Inhibits APP transport to the cell surface and further shedding (PubMed:20427278).
Aliases: C1orf8 antibody, HSPC001 antibody, Liver membrane-bound protein antibody, TMEM59 antibody, TMEM59 transmembrane protein 59 antibody, TMM59_HUMAN antibody, Transmembrane protein 59 antibody
- UniProt
- Q9BXS4
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